ARTICLE
Solvent-Dependent In Vitro Antimicrobial Potential of Aqueous and Ethanolic Extracts of Nicotiana tabacum and Sesamum alatum
Lawrence Luka, Chika Attama
This study evaluates the antimicrobial properties, phytochemical composition, and thin-layer chromatographic (TLC) profiles of aqueous and ethanol leaf extracts of Nicotiana tabacum and Sesamum alatum.
Drug Discovery, 2025, 19(44), e13dd2079
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Antioxidant potential of extracts from Ehretia amoena - A Swazi medicinal plant
Manoharan Karuppiah Pillai1, Noncedo Lomini Sithole1, Justice Mandlenkhosi Thwala1
Ehretia amoena belongs to the Boraginaceae family. E. amoena finds several therapeutic applications in traditional medicine. Nonetheless, its usage in treating human trypanosomiasis (sleeping sickness) and diabetes mellitus is astonishing
Drug Discovery, 2025, 19(44), e14dd2089
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Evaluation of Nano-Carrier Memantine HCl on Alzheimer's disease-induced by D-Galactose and Aluminum Chloride in rats
Vinoth Kumar R, Sankar C, Sivakumar G
Alzheimer's disease (AD) is a, neurodegenerative disorder develop with slow progression. It is featured by memory loss associated with progressive loss of cognitive function was treated with FDA approved Anti-cholinesterase inhibitors
Drug Discovery, 2025, 19(44), e15dd2091
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Optimization of HPMC K4M and Glycerin Concentration in the Formulation of Orally Disintegrating Films of Chlorpheniramine Maleate Using the Solvent Casting Method
Febriyenti F, Regina Andayani, Charrisca Syahyuning Kumalasari
Chlorpheniramine Maleate (CTM) is an alkylamine derivative and antihistamine. It has a relatively short half-life and requires frequent administration, approximately four to six times per day.
Drug Discovery, 2025, 19(44), e16dd2099
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Stability indicating high performance thin layer chromatography method development and validation of Trifluoperazine in bulk and tablet dosage form using a QbD apporach
Shweta R Bharati, Madhuri S Nalawade, Kumudini R Pawar
This research emphasizes use of quality by design framework in conducting a qualitative assessment of Trifluoperazine in both its bulk and tablet forms, with the subsequent development and validation of a high-performance thin layer chromatography technique
Drug Discovery, 2025, 19(44), e17dd2097
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Beetroot juice ameliorates neurotoxicity in the cerebellum following combined ingestion of coffee and Garcinia kola (bitter kola)
Akpanabasi A Malachy, Idorenyin U Umoh, Iboro E Edet
Over the years, the influence of diet on neurological health has been extensively studied, especially regarding the effect of plant materials and beverages on the morphology and function of the brain
Drug Discovery, 2025, 19(44), e18dd2107
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Antioxidant potential of extracts from Allophylus decipiens - A medicinal plant from the Kingdom of Eswatini
Manoharan Karuppiah Pillai, Nkosephayo Mongisi Dlamini, Justice Mandlenkhosi Thwala
Allophylus decipiens belongs to the Sapindaceae family of the genus Allophylus. The species belong to the Allophylus genus have widely been used in the traditional medicine to treat various conditions
