Stucco keratosis is a benign, asymptomatic skin condition characterized by small,
white-to-gray papules, typically observed on the lower extremities of older adults.
It is a relatively common dermatological finding in elderly populations, especially
in males. Nonetheless, it remains under-declared in the literature, with limited
consensus regarding its etiology, pathogenesis, and optimal management. The
clinical importance of stucco keratosis is questionable, including its potential
misdiagnosis as other keratotic lesions, such as seborrheic keratoses or actinic
keratoses. Furthermore, data on effective outcomes and rates of recurrence are
limited. This review aims to summarise current evidence in order to clarify
diagnostic criteria and examine the range of interventions. It also synthesizes and
critically appraises the existing literature on stucco keratosis in terms of
epidemiology, clinical features, differential diagnosis, and treatment approaches.
There are no existing systematic reviews addressing this topic, which underscores
the need for a comprehensive summary. This systematic review includes case
reports, observational studies, clinical trials, clinico-pathological studies, molecular
studies, and reviews related to stucco keratosis. Data from PubMed, Embase, Web
of Science, and Cochrane Library databases on incidence, diagnostic accuracy,
intervention efficacy, and recurrence have been extracted and narratively
synthesized. A better understanding of stucco keratosis may help dermatologists
differentiate it from clinically similar lesions and select appropriate management
strategies, particularly in elderly patients. Findings from this review can support
future research and clinical guidelines.
Keywords: stucco keratosis, keratosis alba, seborrheic keratosis, elderly
dermatology