Volume 29, Issue 162, August 2025

The efficacy and safety of medical cannabis in the management of chronic pain: A systematic review

Paulina Wasilewska^1♦, Paula Klemenska², Weronika Pierudzka³, Józef Sławatycki³, Konrad Warczak³

¹University Clinical Hospital in Poznań, 49 Przybyszewskiego St., 60-355 Poznan, Poland
²Jan Biziel University Hospital No. 2, 75 Kornela Ujejskiego St., 85-168 Bydgoszcz, Poland
³Provincial Hospital in Poznań, 7-19 Juraszów St., 60-479 Poznań, Poland

^♦Corresponding author
Paulina Wasilewska, University Clinical Hospital in Poznan, 49 Przybyszewskiego St., 60- 355 Poznan, Poland

ABSTRACT

Chronic pain is a worldwide health issue that over 20% of word’s population suffer from and it requires evidence-based treatment approaches. Chronic pain remains an unexplained condition that might be caused by biological, psychological and social factors. Managing it effectively is essential for improving the patients’ ability to perform daily activities, enjoy life and maintain independence. It could also mean reducing long-term healthcare costs. Alongside conventional approaches to chronic pain treatment, medical cannabis has become a subject of growing international interest and scientific investigation. The study aimed to assess the safety of medical cannabis as a novel approach to chronic pain treatment.

Keywords: chronic pain, pain management, medical cannabis, analgesia

Medical Science, 2025, 29, e137ms3651

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DOI: https://doi.org/10.54905/disssi.v29i162.e137ms3651

Published: 18 August 2025