Volume 29, Issue 162, August 2025

Endometriosis treatment in the 21st century: current trends and clinical perspectives

Paulina Wasilewska^♦, Olga Wojtczak, Kacper Zagaja, Justyna Wróblewska, Hubert Ziembicki, Natalia Skrzypska

University Clinical Hospital, 49 Przybyszewskiego St, 60-355 Poznań, Poland

^♦Corresponding author
Paulina Wasilewska, University Clinical Hospital, 49 Przybyszewskiego St, 60-355 Poznań, Poland

ABSTRACT

Chronic pelvic pain, infertility, and severe menstrual symptoms are part of everyday life for millions of women around the world. These issues often remain undiagnosed, especially when it comes to endometriosis. Endometrioisis is a multifaceted disease that might be caused by hormonal imbalance, immune dysfunction, microbiome alterations and gene transformation. Managing endometriosis symptoms effectively is essential for patients' quality of life, fertility, and long-term health. In this review, we brought together current ideas on the treatment, considering both long-standing methods and novel approaches.

Keywords: endometriosis, hormonal therapy, microbiome, chronic pelvic pain, estrogen dependence

Medical Science, 2025, 29, e127ms3666

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DOI: https://doi.org/10.54905/disssi.v29i162.e127ms3666

Published: 07 August 2025