Peripheral artery disease (PAD) is a common condition that limits walking and
reduces quality of life. Walking training is now recognized as a key part of
treatment. This review summarizes recent studies on walking-based exercise in
PAD. We researched PubMed for studies published between January 2019 and
March 2025. Only randomized trials, meta-analyses, and systematic reviews were
included. The primary outcomes were walking distance and exercise tolerance.
Moderate-intensity walking improved both pain-free and maximal walking
distances better than vigorous exercise. Walking after stenting helped reduce the
risk of in-stent restenosis. Mobile health tools supported home-based programs
and improved walking ability. Some programs also increased adherence. Effects
on quality of life were mixed. Supervised exercise therapy (SET) was as effective
as revascularization in improving function while being more cost-effective. Home
programs with monitoring worked nearly as well as SET. Blood flow restriction
training and arm ergometry helped patients who could not tolerate walking.
Short and frequent exercise programs were well tolerated and effective, with
satisfying results. SET was found to improve cardiovascular responses and
reduce symptoms of anxiety and depression. Walking training is safe and
flexible. It should be adapted to patient needs. Future work should focus on
adherence and personalizing treatment.
Keywords: Peripheral artery disease, intermittent claudication, walking training,
exercise therapy
