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Volume 29, Issue 157, March 2025

Topical vitamin D as a new acne treatment. A review of the literature

Aleksandra Jonkisz, Seweryn Rozalczyk, Justyna Kowalczewska♦

University Clinical Hospital in Poznan, Poznan University of Medical Sciences, Poznan, Poland

♦Corresponding Author
University Clinical Hospital in Poznan, Poznan University of Medical Sciences, Poznan, Poland

ABSTRACT

Acne vulgaris is a common dermatosis with a complicated and multifactorial basis, occurring in adolescent and adult patients. It is a disease of the pilosebaceous unit. Currently, various treatment regimens are used; the therapy is usually long-term and not consistently effective, and the disease tends to recur. Acne often negatively affects the mental health of patients, both in the active phase and after healing. This is caused by the formation of unsightly scars and discolorations. For this reason, we still need modern drugs in therapy. The antiinflammatory properties of vitamin D3 have long been known. Its topical form is already particularly useful in dermatology in treating psoriasis. This article aims is to analyze the literature describing the use and effectiveness of topical vitamin D3 in the treatment of acne vulgaris.

Keywords: Acne vulgaris, topical vitamin D, topical calcitriol, vitamin D deficiency

Medical Science, 2025, 29, e51ms3545
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DOI: https://doi.org/10.54905/disssi.v29i157.e51ms3545

Published: 15 March 2025

Creative Commons License

© The Author(s) 2025. Open Access. This article is licensed under a Creative Commons Attribution License 4.0 (CC BY 4.0).