Volume 28, Issue 151, Septemper 2024

About the Cover

A lateral neck cyst is a congenital abnormality most commonly occurs in children and young adults. The development of this pathology caused by disturbances during the embryogenesis process, during which there is improper closing of the branchial apertures and incomplete fusion of the branchial arches. This cyst is typically benign- however, in cases of frequent and recurrent infections various complications may arise. A lateral neck cyst can be diagnosed incidentally, for example: during imaging studies to diagnose infection complications. Treatment first involves curing the infections and potential complications, followed by surgical treatment to prevent infection recurrence. Here we describe a case of a patient who presented to the Maxillofacial Surgery Clinic with a sizeable unilateral neck mass measuring approximately 10 cm in diameter, which had been growing asymptomatically for almost four years.

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CASE REPORT

Surgical removal of a giant branchial cleft cyst: A case report

Bernadeta Zabielska, Joanna Kołodziej, Katarzyna Kulej, Agnieszka Krekora-Smolak, Paula Tarkowska, Justyna Perdas, Kinga Kozioł-Wójcik, Barbara Biernacka, Aldona Chloupek

A lateral neck cyst is a congenital abnormality most commonly occurs in children and young adults. The development of this pathology caused by disturbances during the embryogenesis process, during which there is improper closing of the branchial apertures and incomplete fusion of the branchial arches

Medical Science, 2024, 28, e121ms3432

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ARTICLE

Design, fabrication, and in-vitro characterization of pHresponsive sustained-release super porous hydrogel containing metformin HCl

Muhammad Abid Mustafa, Gohar Jaan, Amna Nadeem, Javeria Khan, Javaria Nadeem, Fatima Javed, Maryam Mazhar, Amna Sajjad, Kiran Fatima, Anam Khaliq, Aman Saif, Zarqa Saqib, Muhammad Zahid Iqbal

Objective: The aim of this study is to develop a superporous hydrogel containing metformin HCl that improves patient compliance by providing a convenient dosage regime, reducing the dosing frequency, and decreasing the side effects by providing sustained release. The super porous hydrogel offers a pH-sensitive response.

Medical Science, 2024, 28, e122ms3426

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REVIEW

Botulinum toxin type A in scar treatment: Review article

Alicja Baranowska, Katarzyna Baranowska, Filip Czyżewski, Kinga Filipek, Jakub Kawka, Michał Maciek, Sebastian Mrugała, Waldemar Mrugała, Bartosz Skierkowski, Natalia Zalewska

Introduction: Botulinum toxin type A (BoNTA) has become widely recognized for its expanding abilities of use in various medical fields. Recently, numerous studies and randomized clinical trials have proved its effectiveness in treating postoperative scars, hypertrophic scars, and keloids

Medical Science, 2024, 28, e123ms3436

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What is the relationship between Obstructive Sleep Apnoea and cardiovascular disease? Pathophysiology and therapeutic strategies: A review of the literature

Agata Pisklak, Joanna Sykuła, Natalia Zalewska, Kinga Filipek

Obstructive sleep apnoea (OSA) is a usual sleep disorder affecting millions of people worldwide. This condition is characteristic of recurrent episodes of upper airway obstruction during sleep. This condition results in intermittent hypoxia and also sleep fragmentation.

Medical Science, 2024, 28, e124ms3437

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Macronutrients in context for cancer biology and risk of carcinogenesis

Gustaw Laskowski, Piotr Węgrzyn, Konstancja Węgrzyn, Agnieszka Góra, Marcin Wasilewski, Maciej Nowicki, Julia Skwara, Dawid Barański, Natalia Dąbrowska, Anna Salińska

The incidence of cancer cases is constantly rising despite the continuous development of medical science in this area of interest. Although neoplastic transformation and the mechanisms of tumor cell metabolism have already been widely studied, we still do not know enough how to prevent and treat cancer effectively.

Medical Science, 2024, 28, e125ms3438

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Effect of inspiratory muscle training in pulmonary function and relief of dyspnea in patients with heart failure; systematic review

Abrar Habeeb Bokhamseen, Abeer Ahmed AL-Muhana, Sahar khalid Alkhalifah, Sumayah Hussain Alhuraiz, Aziza Abdullah Alabdullatif, Fatimah Hussain Alkhalaf, Kholoud Hassan ALMarhoun, Noorah Salem Almarri, Hanan Abdullah Alshowkan, Sarah JAffer AL-Ahmed

Background: IMT has already been shown to benefit patients with HF; however, it is unclear which patients benefit most from this intervention and what kind of training is most effective. We aimed to review the impact of IMT on respiratory muscle strength, pulmonary function, functional ability, dyspnea, and Qol in HF patients.

Medical Science, 2024, 28, e126ms3440

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Effectiveness of Pulmonary Rehabilitation in reducing mortality after acute exacerbation of chronic obstructive pulmonary disease; systematic review

Abdulaziz Muncher Alotaibi, Hussein Saleh Alyami, Mohammed Sagheer Albarqi, Osama Ahmed Alshehri, Nasser Mohammed Alhammam, Azizah Hwidi Alkhudairi, Layla Mohammed AlThawadi, Munirah Abdulrahman Almulhim

Background: According to clinical guidelines, patients with COPD can benefit from pulmonary rehabilitation. Our study aim was to assess the effects of an early pulmonary rehabilitation program, initiated within 4 weeks of hospitalization for COPD acute exacerbation, vs standard therapy.

Medical Science, 2024, 28, e127ms3439

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The effect of collaborative care on the progression of diabetic complications in patients with Type II Diabetes Mellitus: A systematic review

Rabeel Khan, Sara Shahid, Ayesha Nadeem, Huzaima Shahzadi, Sumbal Rafique, Muhammad Sheraz, Laraib Abid, Zarqa Saqib, Gulzaib Bibi, Esha Khan, Ayesha Zulfiqar

Background: Type II diabetes significantly affects people worldwide, considerably contributing to the global health burden due to factors such as lifestyle habits, dietary practices, physical inactivity, and genetic factors

Medical Science, 2024, 28, e128ms3342

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ARTICLE

Diabetic patients’ adequacy of knowledge related to insulin injecting techniques and practices. A cross-sectional study from Punjab, Pakistan

Amna Bajwa, Sara Shahid, Minahil Athar, Anosh Sana, Iqra Abid, Shaikh Muhammad Usama Latif, Muhammad Fahad, Maryam Mughal, Maryam Ayesha, Fahad Ahmed, Muhammad Zahid Iqbal

Background: Insulin therapy is considered a vital approach for the therapeutic management of insulin-dependent diabetes mellitus. Various insulin administration devices are available worldwide, among which selfadministration devices are most commonly used

Medical Science, 2024, 28, e129ms3434

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