Objective: To systematically review and explore the impact of neural mobilization
(NM) on pain in patients with sciatica. Methods: Five electronic databases were
searched. Studies investigating NM in patients with sciatica pain using pain
outcome measures mainly to measure potential changes in pain levels. The
studies were assessed using the CONSORT statement checklist. Results: A total of
1581 articles were identified in the search. After the screening process, eight
studies met the inclusion criteria and were included in this review with a total of
368 participants. All the studies measured pain, including the visual analog and
numerical pain rating scales. Seven out of eight studies reported that using NM
impacted sciatica pain significantly (p<0.05) by decreasing the level of pain either
separately (n = 3) or by being combined with other interventions, including hot
packs, exercise therapy, and electrotherapy (n = 4). Conclusion: The studies’
results showed consistency in the evidence that supports using NM to address
sciatica pain when coupled with other interventions. However, conducting a
meta-analysis to measure the effect size of using NM for sciatica pain was not
applicable due to the limited number of studies that measured the discrete effect
of NM on sciatica pain and the clinical heterogeneity in the methodologies of
applying NM in the studies included. Therefore, future studies are advised to
measure the discrete effect of NM by recruiting intervention groups who only
receive NM.
Keywords: Sciatica pain, radiating low back pain, neural mobilization, nerve
mobilization, neurodynamic exercises
