Volume 27, Issue 142, December 2023

Accuracy of preoperative contrast-enhanced ultrasound in grading bladder cancer: Systematic review

Abdullah Hassan Muhayya¹, Raed Abdullah Mohammed², Ahmed Ibrahim A Almania²

¹Urology Consultant, Resident Training Program Director, Asser Central Hospital, Aseer, Saudi Arabia
²Saudi Board Urology resident, Asser Central Hospital, Aseer, Saudi Arabia

ABSTRACT

The second most common type of cancer that urologists treat is bladder cancer, therefore, the best treatment strategies for each patient depend on early detection, accurate staging, and diagnosis. Also, its detection methods should be developed and studied frequently to be improved. This study aimed to assess the utility of contrast-enhanced ultrasound in Bladder cancer diagnosis, particularly in differentiating low-grade from high-grade bladder cancer. The Cochrane Library, EMBASE, and PubMed were used to search the literature until 2022. The criteria for inclusion were studies with patients suspected or unknown bladder cancer undergo contrast-enhanced ultrasound for preoperative diagnosis and local staging based on cystoscopy or transurethral resection. After removal of duplication, abstract and title screening, the review included five studies. Information regarding author name, year of publication, objective, study participant’s characteristics, findings and conclusion were all extracted from the studies. With a mean age ranging from 60 to 68 years, the included publications featured a total of 436 bladder cancer patients. Upon contrast-enhanced ultrasound, 222 bladder cancer lesions were found to be positive, whereas 214 lesions were found to be negative; histology revealed 78 cases of muscle invasive, 118 cases of nonmuscle invasive bladder cancers, 144 cases of high-grade bladder cancer, and 96 cases of low-grade bladder cancer. According to the results of our systematic review, contrast-enhanced ultrasound has a good level of diagnostic accuracy, sensitivity, and specificity.

Keywords: Bladder cancer, ultrasound, diagnosis

Medical Science, 2023, 27, e396ms3271

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DOI: https://doi.org/10.54905/disssi.v27i142.e396ms3271

Published: 29 December 2023