Introduction: MS patients are very likely to commit suicide due to their
medical condition. For this reason, the present study was performed to
predict suicide commitment based on meaning in life and with the mediating
roles of depression and interpersonal needs in patients with MS. Methods: The
present study was a cross-sectional study including all MS patients in Tehran.
Subjects (n=206) were selected using the convenience sampling method. They
completed questionnaires about meaning in life, Beck's depression, Beck's
suicidal ideation, and interpersonal needs. Data were analyzed using SPSS-25
and AMOS software. The path analysis method was used to analyze the data.
Results: Results of the path analysis showed that, in patients with MS,
meaning in life can predict suicide commitment through the help of
mediators, including depression and interpersonal needs (thwarted
belongingness and perceived burdensomeness) death in MS patients. Fit
indices showed that the model has been confirmed. Conclusion: Meaning in
life, depression, and interpersonal needs play pivotal roles in predicting
suicidal behavior in patients with MS; for this reason, these components must
be addressed as therapeutic goals.
Keywords: Suicide, Multiple sclerosis, Thwarted belongingness, Perceived
burdensomeness, Depression
