Volume 27, Issue 140, October 2023

Medical and social characteristics of the main risk factors of the development of gastric cancer in conditions of stress

Tetyana Domanchuk¹, Oryna Detsyk², Zhanetta Chornenka¹, Mariana Hrytsiuk¹, Anzhela Biduchak¹

¹Department of Social Medicine and Public Health, Bukovynian State Medical University, Chernivtsi, Ukraine
²Department of Social Medicine and Public Health, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine

ABSTRACT

Background: Socio-economic and socio-psychological factors associated with the malignancy of precancerous diseases in malignant neoplasms of the stomach negatively affect the material well-being and social activity of patients, limit their life activities due to deterioration of physical and psychological well-being, lead to dissatisfaction with the state of health and to complaints of constant distress against the background of increased value of life itself. Methods: An analytical retrospective epidemiological medicalsociological study of a representative number of patients with gastric malignancies - 130 patients from the leading group and 50 people with precancerous diseases of the stomach from the comparison group - was conducted with the aim an in-depth study of medical and organizational risk factors in the study. Results: Risk factors for malignant transformation of gastric precancerous disease were found to be mostly modified, in addition to uncontrolled: behavioral - unfavorable eating habits: Too frequent meals (OR=5.27; 95% CI=2.59-10.72), excessive intake of sweet foods(3.48; 1.28-9.48), caffeinated beverages (3.37; 1.64-6.92) and alcohol (3.12; 1.44-6.78), insufficient fluid intake (3.04; 1.43-6.45), smoking (2.97; 1.46-6.06), especially intensive (5.80; 1.10-30.50), occupational-industrial hazards of chemical nature and contact (2.30; 1.02-4.20), genetic -hereditary amnesia (5.20; 2.25-12.02) and social - living in rural areas (28.61; 8.44-97.03). Gastrointestinal discomfort (2.93; 1.39-6.18) and weight loss (2.07; 1.07-4.02) were established to be predictors of malignant transformation. Conclusion: The appearance of new malignant neoplasms of the stomach is due to both uncontrollable risk factors and, in the vast majority, modified ones, and stressful situations contribute to the slightest degree of malignancy of precancerous gastric diseases.

Keywords: Gastric cancer, precancerous diseases of the gastric, risk factors, stressful situations

Medical Science, 2023, 27, e368ms3231

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DOI: https://doi.org/10.54905/disssi.v27i140.e368ms3231

Published: 20 October 2023