Medical Science
Volume 26, Issue 130, December 2022
The antimicrobial vulnerability testing of Linum flavum hydrocolloids against pediatric surgical MRSA isolates with qualitative bio-phytochemical analysis quantified by GC-MS-UV-Vis spectrophotometry
Muazzam Sheriff Maqbul1♦, Rayan Nasser Sarhan2, Fatima Aqeel Saeed Alzubaidi3, Aljawhara Talal Hejji4, Mariam Aqeel Saeed Alzubaidi3, Ibrahim Khaled Abdul Baqi3, Sundas Yousef Wali Yousuf4, Raha Mohammed Garout4, Norah Ali Alhasawi5, Wajd Ahmed Aljohani5, Reem Mussaed Aladwani5, Tarteel Mohammad Alaali5, Ameera Tariq Yaghmour6, Afnan Mahmoud Hanbzazah7
1Department of Microbiology and Immunology, Ibn Sina National
College for Medical Studies, Jeddah 21418, KSA
2Department of Pediatric Emergency Medicine, Maternity and Children
Hospital, Makkah, KSA
3Medicine Program, Ibn Sina National College for Medical Studies,
Jeddah 21418, Kingdom of Saudi Arabia
4Medical Intern, King Fahd Hospital, Jeddah, KSA
5Medical Intern, East Jeddah Hospital, Jeddah, KSA
6Medical Intern, Al Jedani Hospital, Jeddah, KSA
7Department of Internal Medicine, King Abdulaziz Hospital
& Oncology Centre, Jeddah, KSA
♦Corresponding author
Department of Microbiology and Immunology, Ibn Sina National College
for Medical Studies, Jeddah 21418,
KSA ORCID: https://orcid.org/ 0000-0002-9400-5528
ABSTRACT
The primary goal of this review was to decide the adequacy of L. flavum
medicinal oil hydrocolloids against MRSA by anti-microbial weakness testing
and decide its phytochemical properties. Linum flavum (Golden Flax seed) is an
herbaceous plant that has long been used since ancient past to combat
pathogens particularly those caused by bacterial, viral and fungal agents. This
study attempted to rediscover the forgotten past by treating the plant
derivative in the form of the hydrocolloids obtained from L. flavum and testing
its antimicrobial vulnerability testing against pediatric surgical isolates of
MRSA and comparing its data with the standard antibiotics available on the
market. The qualitative Kirby-Bauer disc diffusion techniques and the
quantitative standard antimicrobial techniques employed in this study. The
qualitative bio-phytochemicals of L. flavum hydrocolloids was carried out
using standard biochemical tests to detect the presence of phytochemical
components, which were then quantified using GC-MS-UV-Vis
spectrophotometry. The bio-phytochemical nature of L. flavum hydrocolloids
was assessed and the results were promising, along with MRSA vulnerability
test data, proving to be an asset for the phytol-pharmaceutical industries. This
study was to analyze the antibacterial effect of L. flavum oil hydrocolloids
against pediatric surgical isolates of Staphylococcus aurous resistant to methicillin antibiotics (MRSA). This study was also designed to analyze the bio phytochemical properties of L. flavum oil hydrocolloids in order to provide adequate future drug availability for combating dangerous pathogens
Keywords: Antimicrobial, MRSA, GC-MS-UV-Vis spectrophotometry, Linum flavum, Flax Seed
Medical Science, 2022, 26, ms571e2688
DOI: https://doi.org/10.54905/disssi/v26i130/ms571e2688
Published: 27 December 2022
