Background: Hypertension is a common disease in Saudi Arabia. Non adherence to hypertension treatment is a common reason for
failure to reach the target blood pressure. Multiple studies have shown a direct relationship between patients’ knowledge of
hypertension and their adherence level to antihypertensive drugs. Aim: The study’s aim is to identify the association between
hypertension knowledge and adherence to antihypertensive drugs among hypertensive patients in Qassim region. Methods: A cross
sectional study performed in the Family Medicine clinics of Qassim University Medical City. A self-administered questionnaire was
distributed among hypertensive patients. The questionnaire includes socio-demographic characteristics, General Medication
Adherence Scale (GMAS) and Hypertension Knowledge Test (HKT). Results: Of the 452 hypertensive patients, 56.4% were females
and 36.1% were aged between 31 to 50 years old. The overall mean GMAS score was 28.1 (SD 5.15), with 51.3% categorized as
having high adherence. The overall mean HKT score was 12.6 (SD 3.75), wherein 58.4% was considered to have average
hypertension knowledge. There was a notable positive correlation between the GMAS score and the HKT score. Conclusion: Patients
with hypertension in Qassim region showed a high level of adherence to their antihypertensive drugs and only moderate
knowledge of their disease. Greater drug adherence is more common in patients who are aware of their disease than in other
hypertension patients. More investigations are required to determine the level of knowledge and adherence among hypertension
patients in our region.
Keywords: Hypertension, antihypertensive drugs, medication adherence,
hypertension knowledge, Qassim region, Saudi Arabia