Volume 26, Issue 125, July 2022

Diagnostic dilemma of a complex tumor- hemangiopericytoma/ solitary fibrous tumour or nodular hidradenoma of thigh - A unique case report

Pooja Jha^1♦, Samarth Shukla², Sunita Vagha³, Ravindra P Kadu², Sourya Acharya⁴

¹M.D. Pathology Resident (2nd year), Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India
²Professor, Department of Pathology, Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India
³Professor and Head, Department of Pathology, Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India
⁴Professor and Head, Department of Pathology, Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India
⁵Professor and Head, Department of Medicine, Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India

^♦Corresponding author
M.D. Pathology Resident (2nd year), Jawaharlal Nehru Medical College (DMIMS), Sawangi (M), Wardha, India

ABSTRACT

Hemangiopericytoma is described as a rare variety of tumors originating from the unrestricted or uncontrolled proliferation of pericytes. It is believed that these rare tumors arise from the vascular cells called Zimmerman pericytes which are present in the entire spiral body involving the capillaries and post-capillary venules. These painless, slowly growing tumors are liable to develop in the subcutaneous tissue and skeletal muscle. Hemangiopericytomas more commonly affect the lower extremities and may also affect the head and neck region. Clinically, it can affect any age but the increased incidence has been noted in adults in the fifth decade of life without any gender predilection. We report a case of hemangiopericytoma of the left lower extremity i.e., in the thigh in a 35-year-old male patient who came to our hospital at J.N.M.C., Sawangi (M), Wardha with the chief complaints of a painless mass in the left thigh which clinically looked like a sebaceous cyst. Thereafter, tumor excision was performed and the sample was sent for HPE. The histopathological examination of the tumor tissue showed features that were highly suggestive of hemangiopericytoma. However, interestingly the tumor was diagnosed as Nodular Hidradenoma, a benign adnexal tumor on immunohistochemistry. Nodular hidradenoma is a rare non-malignant tumor of adnexa that originates from the distal excretory duct of eccrine or apocrine sweat glands, which is rare, considering all the adnexal tumors.

Keywords: Hemangiopericytoma, pericytes, benign mesenchymal tumors, solitary fibrous tumors, nodular hidradenoma

Medical Science, 2022, 26, ms278e2285

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DOI: https://doi.org/10.54905/disssi/v26i125/ms278e2285

Published: 14 July 2022