Introduction: Respiratory tract infections consist of many diseases such as colds, pharyngitis, tonsillitis, influenza and respiratory diseases. Therefore, this meta-analysis study was performed to assay the effect of zinc, selenium, vitamin D, vitamin C on respiratory tract infections. Methods: In this systematic review of data on the effects of zinc, selenium, vitamin D and vitamin C on respiratory tract infections in the last 20 years in the world (2011-2001) with a review of 30 studies (5351 cases) including English and Persian articles, Reputable domestic and foreign sites were performed. Data were analyzed using meta-analysis. Finding: The odds ratio of respiratory tract infections in vitamin D users was estimated to be 0.797 (confidence interval 95%, 0.808-0.786). The Rate of odds of respiratory infections in consumers of vitamin C, 0.0496 (confidence interval 95%, 0.55-1.441) was estimated. The odds ratio of respiratory infections in zinc users was estimated to be 0.437 (confidence interval 95, 0.51-0.366). The odds ratio of respiratory tract infections in selenium users was estimated to be 0.624 (confidence interval 95, 0.696, 0.545). Results: Respiratory infections are seen in consumers of vitamin D, vitamin C, zinc, selenium. Proper use of vitamin D, vitamin C, zinc, and selenium is essential in addition to monitoring the epidemiology of regional respiratory infections.
Keywords: Vitamin D, vitamin C, zinc, selenium, respiratory infections