Volume 26, Issue 119, January 2022

Cardiovascular risk factors and co-morbidities in patients with Alopecia Areata: A case-control study

Dalia A Ahmed Attallah¹, Mahmoud Ali M Ashry², Samah Abourehab¹, Ayman M Mahran^1♦

¹Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt
²Department of Internal Medicine and Cardiology, Faculty of Medicine, Assiut University, Assiut, Egypt

^♦Corresponding author
Assistant Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Egypt

ABSTRACT

Objective: Study the possible cardiovascular risk factors and co-morbidities in patients with Alopecia Areata. Design: Case-control study. Setting: Dermatology Outpatients' Clinic, Assiut University Hospitals, Egypt. Patients and Methods: One hundred Alopecia Areata patients and fifty age and sex matched healthy controls were recruited from the Dermatology Outpatients’ Clinic, Assiut University Hospitals, Egypt at the time from June 2018 to January 2020. Each participant was exposed to full history taking, general and dermatological clinical examinations, Severity of Alopecia Tool score and Body Mass Index evaluation. Investigations included Complete Blood Count, Lipogram, random blood sugar, Electrocardiogram and Echocardiography. Results: Body Mass Index of patients was significantly higher than that of the controls. Patients had significantly lower levels of hemoglobin. Triglycerides, Cholesterol and Low Density Lipoproteins levels were significantly higher in patients. However, High Density Lipoproteins levels were significantly lower in patients. Positive correlations were detected between SALT score with Triglycerides, Cholesterol, Low Density Lipoproteins and random blood glucose. No definite ECG or ECHO abnormalities could be identified in patients. Conclusion: Patients with Alopecia Areata, especially severe forms, have several CV risk factors which make them liable for future development of definite CV diseases.

Keywords: Alopecia Areata, Cardiovascular comorbidities, SALT score

Medical Science, 2022, 26, ms37e1866

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DOI: https://doi.org/10.54905/disssi/v26i119/ms37e1866

Published: 19 January 2022