Volume 25, Issue 117, November 2021

Ultrasonography in diagnosis of amyloidosis of thyroid gland: Rare case

Rania Mohammed Ahmed^♦

Associate prof, Radiological Sciences Department, Applied Medical College, Taif University. Saudi Arabia.

^♦Corresponding author
Dr. Rania Mohammed Ahmed, Associate prof, Radiological Sciences Department, Applied Medical College, Taif University. Saudi Arabia.

ABSTRACT

Introduction: Amyloid goiter is a very rare manifestation of amyloidosis, can occur as a result of either primary or secondary amyloidosis of unknown etiology, leading in an increase in the size of the thyroid gland and compressive symptoms, depending on deposit location and severity. Case presentation: We report a case of 17-year-old patient who came with a one year history of enlarging painless neck and face swelling, presented to the Endocrine department in Tadawi international Poly Clinics in Abha City, Aseer Area, South of Kingdom Saudi Arabia. An enlarged thyroid gland with mediastinal involvement was discovered on ultrasound. The patient was diagnosed with primary amyloidosis involving only the thyroid gland, which was confirmed by histopathology. The multinodular appearance was compatible with a diagnosis of multinodular goiter. Discussion and conclusion: Amyloid Goiter is an extremely uncommon condition. Many previous studies revealed that a strong index of suspicion is expected in individuals with enlarged thyroid glands and a history of persistent inflammatory processes or plasma cell disorders. Fine needle aspiration cytology/biopsy (FNAC/B) should be undertaken to rule out thyroid cancer. Thyroidectomy is required for a variety of reasons; such as confirmed diagnosis cases.

Keywords: Amyloidosis, Thyroid, Ultrasound, Male, Goiter, KSA

Medical Science, 2021, 25(117), 2765-2768

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