Volume 25, Issue 117, November 2021

Effect of nebulized furosemide in patients with acute asthma in Iraq

Abdullah Arnus Abdul-Hassan^1♦, Hashim M Hashim²

¹Department of Medicine Al-Immamain Alkadhmain medical city, Baghdad, Iraq
²Department of Medicine College of Medicine Al-Nahrain University, Baghdad, Iraq

^♦Corresponding author
Department of Medicine Al-Immamain Alkadhmain medical city, Baghdad, Iraq

ABSTRACT

Objective: Identify whether nebulized frusemide has any therapeutic benefit in patients with acute attack of asthma. Methods: A total of 24 patients were diagnosed with acute asthma; 12 of them were given nebulized frusemide 40mg and the other 12 patients were given nebulized saline as control. Every patient in the two groups has FEV1 measured before and after the test and received IV aminophylline over 60 minutes on admission and before the test. Results: a mean increase in the FEV1 of 27.6 ± 9.1 in the furosemide group while there is a mean in the FEV1 of 4.8 ± 4.4 in the other group. These changes are regarded as statistically significant (P value <0.005). Conclusions: When it comes to patients with severe asthma, receiving IV aminophylline, the use of nebulized frusemide produced significant improvement in the FEV1.

Keywords: frusemide, inhalation, nebulizer, pulmonary function test

Medical Science, 2021, 25(117), 2822-2826

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