Medical Science
Volume 25, Issue 113, July 2021
Antioxidant action of green tea extract in alloxan-induced diabetic albino rats: An experimental laboratory-based study
Ali Hassan A Ali1,2♦, Ali Yaqoub Alali3, Rasheed A Alhajri3, Abdulrahman M Aldawsari3, Ammar H AlHeseni3, Nasser S Aldosari3
1Anatomy Department, College of Medicine, Prince Sattam Bin
Abdulaziz University, Alkharj 11942, KSA
2Anatomy Department, Faculty of Medicine, Al-Azhar University, Cairo,
Egypt
3College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj,
KSA
♦Corresponding author
Anatomy Department, College of Medicine, Prince Sattam Bin Abdulaziz
University, Alkharj 11942, KSA
Anatomy Department, Faculty of Medicine, Al-Azhar University, Cairo,
Egypt
ABSTRACT
Background: Green tea extract can regulate blood sugar and encourage weight loss due to its high antioxidant content. Several studies have shown that green tea extract can improve general health and may help protect against many diseases. Most patients with diabetes are associated with poor fertility. Aim of the work: The present study aimed to evaluate the importance of green tea extract supplementation in reducing metabolic abnormalities associated with alloxan-induced diabetes in male albino rats. Material and Methods: The number of male rats was thirty, weighing 100-110 grams were used in the current study. The rats were divided equally into three groups that included control, diabetic and diabetic took green tea extracts orally (50 mg/Kg/day) for three weeks. To induce diabetes one dose (120 mg/kg) of alloxan was used. Diabetic rats were given “50 mg/kg body weight green tea extracts orally for thirty days twice per day. The morphological and histological structures of the testis were compared in different groups of the rats. Results: It was revealed that the morphological changes of the testis observed in diabetic groups were siginficantly improved after treatment with green tea compared to the control group. Conclusion: These results prove that green tea improves oxidative damage caused by diabetes in the testis of male rats.
Keywords: Testis, green tea, Antioxidant, alloxan, Albino rat.
Medical Science, 2021, 25(113), 1542-1550
