Volume 25, Issue 110, April, 2021

Preoperative immature granulocyte count and percentage for complicated acute appendicitis and uncomplicated acute appendicitis (A retrospective cohort study)

Mehmet Buğra Bozan^1♦, Fatih Mehmet Yazar², Özlem Güler³, Ayşe Azak Bozan⁴, Ömer Faruk Boran⁵

¹Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Surgery, Kahramanmaraş/Turkey; ORCID:0000-0001-5573-2645; Email: bbozan@yahoo.com
²Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Surgery, Kahramanmaraş/Turkey; ORCID:0000-0002-1780-6962; Email: fmyazar@hotmail.com
³Professor (Assistant), Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Emergency Medicine, Kahramanmaraş/Turkey; ORCID: 0000-0002-1444- 7730; Email: ozlemguler81@yahoo.com
⁴NecipFazıl State Hospital, Department of Anesthesiology and Reanimation, Kahramanmaraş/ Turkey; ORCID: 0000-0001- 8737-4408; Email: ayseazak23@hotmail.com
⁵Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Kahramanmaraş/ Turkey; ORCID:0000-0002-0262-9385; Email: omerfarukboran@hotmail.com

^♦Corresponding author
Kahramanmaraş Sütçü İmam University, Faculty of Medicine, Department of Surgery, Kahramanmaraş/Turkey; Email: bbozan@yahoo.com

ABSTRACT

Aim: Complicated acute appendicitis causes prolonged hospitalisation and increased risk of complications. Preoperative differentiation of this case can help us to select appropriate treatment options (surgery or medical treatment). In this retrospective cohort study it is aimed to evaluate the preoperative immature granulocyte count (IGC) and percentage (IGP) in differentiation of complicated and uncomplicated acute appendicitis cases. Methods: 70 of 156 patients who were operated with the same surgical team for acute appendicitis between June 2018 – June 2019 included into this study. Demographic data (age, sex), white blood cell count (WBC), Neutrophil-Lymphocyte Ratio (NLR), IGC and IGP of complicated acute appendicitis (Group C) cases and uncomplicated acute appendicitis (Group UC) cases were evaluated retrospectively. Results: Male/Female rate was 40/30 (%57.1/%42.9). The count of cases for Group C and Group UC was 25/45 (%35.7/ %65.3). Between Group C and Group UC, there was no statistically significant difference for age and sex (p>0.05); there was statistically significant difference for WBC, NLR IGC and IGP (p<0.05). A multivariant analysis of the effective factors shows that both of the factors WBC, NLR, IGC and IGP are predictive for complicated acute appendicitis cases (p value <0.001 for both of the factors). Conclusion: The IGC and IGP obtained from the complete blood count test are sensitive predictive factors with the other inflammatory parameters to make a differential diagnosis between uncomplicated and complicated acute appendicitis. As a result IGC and IGP can be useful for guidance of nonoperative management of acute appendicitis.

Keywords: Acute Appendicitis, Complicated Acute Appendicitis, Emergent Surgery, Immature Granulocyte Count, Immature Granulocyte Percentage

Medical Science, 2021, 25(110), 760-766

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