Volume 25, Issue 109, March, 2021

Comparison of the diagnostic precision for ultrasound and mammogram in dense breasts tissue of young females

Mahmoud H Alkhasawneh^1♦, Asma’a Al-Mnayyis², Maria Alawi³, Ekatereena Obaisat⁴, Eman M Alzyoud⁵

¹Division of Radiology, Faculty of Medicine, Mutah University, Alkarak, Jordan; Email: mahmoudalkasawneh@yahoo.com
²Department of Clinical Sciences, Faculty of Medicine, Yarmouk University, Jordan; Email: asmaa.mnayyis@yu.edu.jo
³Alkarak Tertiary Teaching Hospital, Ministry of Health, Jordan; Email: mariaalawi1979@gmail.com
⁴Alkarak Tertiary Teaching Hospital, Ministry of Health, Jordan; Email: dr_katreenobaisat@yahoo.com
⁵Sixth year student, Faculty of Medicine, Mutah University, Alkarak, Jordan; Email: emansameer14@gmail.com

^♦Corresponding author
Division of Radiology, Faculty of Medicine, Mutah University, Alkarak, Jordan; Email: mahmoudalkasawneh@yahoo.com

ABSTRACT

Background: Globally, breast cancer accounts for a third of womens’ cancer cases. It is experinced in 1-3% of females with clinical breast findings, negative mammogram and ultrasound. Aim: This retrospective study aimed to compare the diagnostic precision of mammogram and ultrasound in detecting breast malignancy. Patients and methods: 332 females from the southern region of Jordan 34-75 years old were enrolled in the study. They were subjected to clinical examination, mammogram, ultrasound and histopathological study for their breast masses at Alkarak teaching hospital. The differential diagnostic precision of both imaging modalities were analyzed in terms of breast density and patient’s age. Based on the breast imaging reporting and data system, mammograms were analyzed into five diagnostic categories (1-5), four grades of breast tissue density (I-IV), while, ultrasound diagnosis was based on five diagnostic categories of the same system. Results: The histopathological examination showed 155 (19.4%) malignant and 177 (4.5%) benign lesions. All malignancies were diagnosed by ultrasound and mammogram, respectively. The obtained results showed statistically significant difference of sensitivies and specificities between the overall ultrasound and mammogram (P<0.05). Regarding breast tissue density, mammogram sensitivity was 83.3% and 0% in grade I and grade IV, respectively. It was 66.7% and 40% in the same grades for ultrasound. Conclusion: The diagnostic precision of ultrasound in differentiating between benign and malignant lesions was significantly higher than mammogram in young Patients with clinical breast findings and dense breast tissue.

Keywords: breast, benign, malignant, diagnostic precision, mammogram, ultrasound

Medical Science, 2021, 25(109), 577-583

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