Objectives: Determine the effective of implementation of the patient education regarding the self-inject of ovarian stimulation
medication at home. Methods: The quasi-experimental study evaluating the program before and after the education intervention
was carried out on 139 patients with assisted reproductive treatment at the Infertility Department, Tu Du Hospital from November 1,
2019 to May 31, 2020. Results: The proportion of patients who agree to self-inject at home is 92.05%. After being instructed by
nurses, 79.1% of patients practice the correct injection in front of nurses. Patients with education upper high school level were able
to inject the right technique 8.38 times higher than patients with education level ≤ high school (OR = 8.38; p <0.05; 95% CI: 2.61-
34.86). If the patients injected the right technique in front of nurses after training, they would be reduced the difficulty when they
performed at home by 82% (OR = 0.18; p <0.05; CI: 0.03-0.93). Patients who have the help of relatives feel more favourable than
those without support of relatives when injected at home is 90% (OR = 0.10; p <0.05; 95% CI: 0.01-0.53). Conclusion: Patients believe
that self-injection at home is easy and acceptable. However, it is necessary to train slowly and more carefully in patients with low
education. At the same time, nurses should persuade relatives to help patients to self-inject at home.
Keywords: Ovarian stimulation, intrauterine insemination, in vitro fertilization.