Volume 24, Issue 106, November - December, 2020

Investigating the effect of topical marcain 0.25% and lidocaine 2% on pain relief following herniorrafia

Arash Azadmehr¹, Hamidreza Khorshidi^2♦, Mohammad Reza Sobhiyeh³

¹Assistant Professor of Thoracic Surgery, Department of General Surgery, School of Medicine, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
²Associate Professor of Thoracic Surgery, Department of Surgery, School of Medicine, Besat Hospital, Hamadan University of Medical Sciences, Iran
³Associate Professor of Vascular Surgery, Department of General Surgery, School of Medicine Taleghani Hospital, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran

^♦Corresponding author
Associate Professor of Thoracic Surgery, Department of Surgery, School of Medicine, Besat Hospital, Hamadan University of Medical Sciences, Iran

ABSTRACT

Introduction: Pain is one of the major postoperative problems, and lack of proper pain management can lead to complications such as increased hospital stay, increased recovery time and more medical costs. There are several methods used to control postoperative pain, the most common of which are administration of analgesics and local anaesthetics at the site of surgery. Therefore, considering the reported side effects, this study tends to investigate the effect of two local anesthetic methods in patients undergoing herniorrafia. Materials & Methods: This study was performed as a clinical trial on 60 patients undergoing herniorrafia in Shariati Hospital of Tehran in 2018. All patients underwent general anesthesia and Liechtenstein. Patients were randomly divided into three groups: marcain, lidocaine, and control. Then, severity of pain was assessed based on VAS after one hour, in the afternoon on the operation day and the day after the operation. Frequency of prescribing pethidine was recorded based on VAS. Statistical analysis of the collected data was performed by one way ANOVA. Results: Three groups were not significantly different in terms of age. Pairwise comparison of groups revealed that severity of pain at the end of surgery and in the afternoon of the operation day was significantly different between marcain group and lidocaine group as well as postoperative marcain group and the control group (P=0.001); however, pain severity was not significantly different between lidocaine and control groups. Conclusion: marcain administration at the surgical incision site compared to lidocaine reduces pain severity and reduces the average administration of pethidine in patients.

Keywords: Herniorrafia, Marcain, Lidocaine

Medical Science, 2020, 24(106), 4368-4373

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