Volume 24, Issue 106, November - December, 2020

Urothelial carcinoma in young adults-Single centre experience

Sharma Vikas^1♦, Bargotya Mona², Gulati Smita³, Yadav Rahul⁴, Faridi Shazib¹, Das Payel², Singh Dinesh¹, Agarwal Ankur¹, Khan Rafey¹, Mallick Kshitij¹

¹Department of Urology, Rajiv Gandhi Superspeciality Hospital, Tahirpur, New Delhi, India
²Deptment of Pathology, Rajiv Gandhi Superspeciality Hospital, Tahirpur, New Delhi, India
³Department of Anesthesia and Pain Clinic, Rajiv Gandhi Superspeciality Hospital, Tahirpur, New Delhi, India
⁴Department of Urology, Apollo Medics Hospital, Lucknow, UP, India

^♦Corresponding author
Dr. Sharma Vikas, Department of Urology, Rajiv Gandhi Superspeciality Hospital, Tahirpur, New Delhi, India

ABSTRACT

Introduction: Bladder cancer has been one of the most common urological malignancies. As per Indian cancer registry data, it is ninth most common cancer among men. Debate exists in the literature regarding the clinical behavior of bladder urothelial neoplasms in younger patients when compared with older patients. In this study, we share our experience with the clinical behavior of the disease in young adults. Materials and Methods: From August 2017 to Feb 2020, data was retrospectively collected from the hospital information system on urinary bladder cancer patients. All Patients presented as bladder mass on radiological investigation underwent transurethral resection of the bladder tumor (TURBT). Pathological grading of the bladder tumour was done by using new World Health Organization (WHO) and International Society of Urological Pathology (ISUP) Classifications. Results: A total of 27 young adults were included in the study who patients presented with bladder cancer. Non-muscle invasive disease was more common as compared to muscle invasive disease. A total of 6 patients underwent a radical cystectomy and standard pelvic lymph node dissection with urinary diversion. 9 patients were put on Bacillus Calmette-Guérin (BCG). Remaining patients were treated as per their histological features. Conclusion: Bladder cancer in young adult population usually presents as urothelial carcinoma with spectrum of bladder carcinoma similar to adult population and should be offered same management as adults.

Keywords: Bladder tumour, Young adults, TCC Urinary Bladder

Medical Science, 2020, 24(106), 3967-3971

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