Volume 24, Issue 105, September - October, 2020

Therapeutic marks of the acute coronary syndrome: a single-center familiarity

Hussain Gadelkarim Ahmed^1,2♦, Hamad Fahad Jarallah Aljarallah³, Abdulrahman Abdulaziz Abdulrahman Aljarallah³, Kheder Mohamed Altayep⁴

¹Department of Pathology, College of Medicine, University of Ha’il, Saudi Arabia
²Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan
³College of pharmacy, University of Ha’il, Saudi Arabia
⁴Department of Medicine, King Khalid Hospital, Hail, Saudi Arabia

^♦Corresponding author
Prof. Hussain Gadelkarim Ahmed, College of Medicine, University of Ha’il, Saudi Arabia; Email: hussaingad5@gmail.com

ABSTRACT

Background: Acute coronary syndrome is a major health concern with an increase in the sedentary lifestyle in Saudi Arabia. With the spectrum ACS clinical presentations, choosing an appropriate treatment guideline is a challenge. Therefore, this study aimed to explore the therapeutic marks of ACS in a Single-center acquaintance. Methodology: Information regarding 156 ACS patients were re-claimed from King Khalid hospital, Ha’il, Northern Saudi Arabia. All patients were admitted to the hospital during a year period and diagnosed as having ACS. Results: Most of the patients in the study were presenting with STEMI followed by NSTEMI and unstable angina, representing 83/156(53%), 43/156(28%), and 30/156(19%), respectively. For males, the most common ACS type was STEMI 69/130(83%) followed by NSTEMI 38/130(29%), whereas, STEMI 17/26(65%) was the most common type in females followed by unstable angina 7/26(27%). The risk of NSTEMI associated with males, the relative risk (RR) and the 95% confidence interval (CI) was; RR (95%CI) = 1.52 (0.6615 to 3.4926), P = 0.3239, z statistic = 0.986. The risk of unstable angina associated with females, the RR (95%CI) = 1.5217 (0.7305 to 3.1699), P = 0.2621, z statistic = 1.121. Conclusion: ACS is prevalent in Northern Saudi with the most common types of STEMI followed by NSTEMI and unstable angina. Males are more susceptible to the disease than females. The therapeutic targets involved in the management of patients are in aligned with the globally used guidelines with the expectation of the absence of Ticagrelor and Prasugrel antiplatelet regime.

Keywords: Acute coronary syndrome, NSTEMI, STEMI, unstable angina, Saudi Arabia, therapeutic

Medical Science, 2020, 24(105), 2802-2811

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