Volume 24, Issue 105, September - October, 2020

An unusual neurological complication of Desmopressin: A case report

Reem Alyoubi

Assistant Professor of Pediatric Neurology, Epilepsy and Clinical Neurophysiology, Division of Neurology, Department of Pediatric, King Abdulaziz University Hospital, Jeddah, Saudi Arabia; Email: raalyoubi@kau.edu.sa

ABSTRACT

Desmopressin is generally used to treat nocturnal enuresis but is not recommended for pediatric patients due to reports of seizures caused by an electrolyte imbalance. This case report is on a 10-year-old Yemeni male patient who suffered four seizures after using intranasal desmopressin for one month without proper supervision. Some studies have proven that the usage of intranasal desmopressin can have adverse effects. The major side effect concerning our case was the seizures, which were due to an electrolyte imbalance resulting in hyponatremia. As a result, patients must take precautions while on this medication. In conclusion, parents must be counseled about the side effects of intranasal desmopressin in order to help them make a well-informed decision when obtaining this medication. If they decide to use it, they should administer the doses under supervision.

Keywords: Desmopressin; seizures; pediatric patient; electrolyte imbalance; complication

Medical Science, 2020, 24(105), 3705-3708

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