Volume 24, Issue 104, July - August, 2020

Using 75 g OGTT in prediction for antenatal insulin need in gestational diabetes mellitus in hung Vuong hospital, Vietnam

Huynh Nguyen Khanh Trang¹, Hoang Thi Diem Tuyet², Nguyen Sy Quang³, Ngo Minh Xuan^4♦

¹Pham Ngoc Thach University of Medicine, Vietnam
²Hung Vuong hospital of obstetrics and gynecology, Vietnam
³Ho Chi Minh City University of Medicine and Pharmacy, Vietnam
⁴Pham Ngoc Thach University of Medicine, Vietnam

^♦Corresponding author
Pham Ngoc Thach University of Medicine, Vietnam; Email: xuanlien62@pnt.edu.vn

ABSTRACT

Gestational diabetes mellitus (GDM) is on the rise in the world and Vietnam. Primary intervention was a modest diet; some recent studies have documented the high blood glucose level in 75 grams glucose tolerance testing associated with simple dietary control failure. Objectives: To determine the relationship between the level fasting plasma glucose in 75 grams of glucose tolerance test and the needs of insulin therapy in gestational diabetes mellitus at the Department of High-Risk pregnancy, Hung Vuong hospital. Methods: A nested case-control study including 160 pregnant women with GDM treated at the Department of High-Risk pregnancy, Hung Vuong Hospital, HCMC from 11/2017 to 11/2019, were eligible for sampling and consent to participate. Results: Fasting plasma glucose, 1 hour after ingestion, and 2 hours after ingestion in the 75 grams glucose test were significantly higher in the gestational diabetes mellitus group with insulin compared with the control group diet. Conclusion: Fasting plasma glucose values in the 75-gram glucose test - 2 hours can help predict the need for insulin in pregnant women with GDM.

Keywords: gestational diabetes mellitus, simple dietary, fasting plasma glucose, nested case-control study.

Medical Science, 2020, 24(104), 2526-2530

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