Volume 24, Issue 104, July - August, 2020

Relationship between acute kidney injury and some surgical interventions and the effects of medicine in premature infants at Children’s Hospital 1

Ngo Minh Xuan

Pham Ngoc Thach University of Medicine, Vietnam; Email: xuanlien62@pnt.edu.vn

ABSTRACT

Objective: Determining the relationship between acute kidney damage and some surgical interventions and the effects of nephrotoxic drugs in premature infants at the Children’s Hospital 1. Object and method: A cross-sectional study describing a series of analyzes involving 20 premature infants with acute kidney injury and 120 premature infants without acute kidney injury met the criteria for joining the department of neonatal resuscitation at the Children’s Hospital 1 from September 2017 to May 2018. Results: PDA surgery and general surgery are not associated with acute kidney damage. The use of antibiotics has the potential to affect kidney function: Amikacin, Vancomycin, and Amphotericin B are all associated with acute kidney damage (p <0.05). The group with acute kidney damage had a higher death rate than the group without acute kidney damage (p <0.001). Conclusion: there is the relationship between acute kidney damage and the effects of antibiotics on premature infants.

Keywords: acute kidney injury, premature infants, surgical interventions, drugs

Medical Science, 2020, 24(104), 2362-2365

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