Medical Science
Volume 24, Issue 104, July - August, 2020
Role of computed tomography in post-chemotherapy evaluation of neuroblastoma in children
Pham Xuan Dung1, Nguyen Thi Phương2, Huynh Quang Huy3♦, Nguyen Huu Chi4, Nguyen Thanh Hiep5
1Ho Chi Minh City Oncology Hospital, Vietnam
2Ho Chi Minh City Children's Hospital 2, Vietnam
3Radiology department, Pham Ngoc Thach University of Medicine, Vietnam; Email: huyhq@pnt.edu.vn
4Ho Chi Minh City Children's Hospital 1, Vietnam
5Pham Ngoc Thach University of Medicine, Vietnam
♦Corresponding author
Radiology department,
Pham Ngoc Thach University of Medicine,
Vietnam;
Email: huyhq@pnt.edu.vn
ABSTRACT
Background: Neuroblastoma is the most common type of cancer that accounts for 15% of all mortality in children. Imaging diagnosis
takes an essential role in the detection, diagnosis, follow of tumors, and so does Computer tomography. This study determines the
value of Computer tomographic in the evaluation of neuroblastoma in children after chemotherapy. Methods: 49 pediatric patients
were diagnosed neuroblastoma at the Children Hospital 2 Ho Chi Minh City from February 2015 to January 2017. The patients were
treated with chemotherapy. The study was designed with prospective analysis. Tools and means of study: CT images were taken by
the "CT Light Speed" machine with eight probe ranges of GE incorporation, USA. Results: 49 cases of neuroblastoma, of which 22
had follow-up by Computer tomographic after chemotherapy. The rate of under-five children is 89.9%. Boys are more likely than
girls with a rate of 1.33/1. Tumor at stage III, IV accounted for 71.5%. Histopathology is characterized by non-differentiated disease
(87%). Computer tomography has been shown to play an important role in evaluating tumor size, crossing the middle line, blood
vessels, pushing organs, invading neighboring neurons before and after chemotherapy. Conclusion: Computed tomographic study is
useful to evaluate the neuroblastoma after chemotherapy.
Keywords: Computer tomographic, Wilms’ tumor, children
Medical Science, 2020, 24(104), 2329-2334
