Volume 24, Issue 104, July - August, 2020

Early fluid aspiration among cesarean section scar deficiency reduces cancellation rate and increase the clinical pregnancy rate among patients undergoing frozen embryo transfer

Hoang Thi Diem Tuyet¹, Huynh Nguyen Khanh Trang², Ngo Minh Xuan^2♦

¹Hung Vuong Hospital of Obstetrics and Gynecology, Ho Chi Minh city, Vietnam
²Pham Ngoc Thach University of Medicine, Ho Chi Minh city, Vietnam

^♦Corresponding author
Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam; Email: xuanlien62@pnt.edu.vn

ABSTRACT

Background: Invitro fertility (IVF) has been set up in Vietnam since 1998. Upto now, all over Vietnam, we have 26 centers of IVF with more than 2000 babies per year. Almost all IVF pregnancies have been terminated by Cesarean sections (C section) in Vietnam. Deficient C section scars sometimes make it very difficult for frozen embryo transfer because of both endometrium development and the fluid inside the uterus cavity. This study aims to identify whether early fluid aspiration among C section scar deficiency reduces cancellation rate and increase the clinical pregnancy rate or not among patients undergoing frozen embryo transfer. Methods: We analyzed thirty-six cases with C section scar impaired followed endometrium preparation before frozen embryo transfer at Hung Vuong hospital – Ho Chi Minh city- Vietnam, from January 2016 to January 2019. All participants have all the inclusive criteria of the study. Results: The average age of participants is 37± two years. 30.5% are residents of Ho Chi Minh City, others living in other provinces of Vietnam from North to South. 15/36 (41.7%) participants have had a C section before going through IVF. 15/36 (41.7%) have C section by obstetric in other provinces. All 36 cases were aspirated early from the 7th day of endometrial preparation, 22/36 (61.1%) were second-hand suction on day 14 of uterine endometriosis, and 5 / 36 (13.9%) smoke the third time on the 21st day of endometrial preparation. In 36 cases participating in the study, 05 cases did not meet the criteria of embryo transfer, so the cycle was canceled, with the rate of cancellation of 5/36 (13.8%) much lower than the previous intervention with Antibiotics and anti-inflammatory (40%). The pregnancy rate is 16/31 (51.6%), and the clinical pregnancy rate is 14/31 (45.2%), which is equivalent to the general pregnancy, and clinical pregnancy rate of embryo transfer at Infertility department of Hung Vuong Hospital. Conclusion: Early intrauterine fluid aspiration during endometrial preparation in frozen embryo transfer patients with C section scar failure reduced the cancellation rate and increased pregnancy and clinical pregnancy rates in this patient group but also need more research in the future.

Keywords: C section scar failure, intrauterine fluid aspiration, assisted reproduction

Medical Science, 2020, 24(104), 2131-2136

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