Volume 24, Issue 104, July - August, 2020

Primary systemic amyloidosis with peripheral and autonomic neuropathy presenting as recurrent presyncope: A case report

Amol Andhale¹, Sourya Acharya^2♦, Samarth Shukla³

¹Resident, Dept. of Medicine, DMIMSU (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
²Professor, Dept. of Medicine, DMIMSU (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
³Professor, Dept. of Pathology, DMIMSU (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India

^♦Corresponding author
Professor, Dept. of Medicine, DMIMSU (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India; Email: souryaacharya74@gmail.com

ABSTRACT

Amyloidosis may occur as a familial disorder with dominant inheritance or as non-familial variant. Non familial amyloidosis is further divided into primary amyloidosis, which occurs in the absence of other disorders but usually associated with multiple myeloma; and secondary amyloidosis in association with disorders such as chronic infections and rheumatologic diseases. Only primary and familial amyloidosis is commonly associated with a polyneuropathy. We present a case of a fifty-one year old female who presented with recurrent pre syncopal attacks and neuropathy, and later on diagnosed as primary systemic amyloidosis.

Keywords: amyloidosis, familial, rheumatologic, polyneuropathy, infections

Medical Science, 2020, 24(104), 1818-1821

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