Volume 24, Issue 103, May - June, 2020

Randomized trial on weight and lipid profile of obese by formulation from Garcinia cambogia

Raja M¹, Chintamani Nayak², Biswaranjan Paital^3♦, Prasanta Rath⁴, Karunakara Moorthy⁵, Sobiya Raj⁶, AK Hati⁷

¹Department of Homoeopathic Pharmacy, National Institute of Homoeopathy, Block GE, Sector-III, Saltlake, Kolkata
²Department of Materica Medica, National Institute of Homoeopathy, Block GE, Sector-III, Saltlake, Kolkata
³Redox Regulation Laboratory, Department of Zoology, CBSH, Odisha University of Agriculture and Technology, Bhubaneswar, Odisha, India
⁴Department of community Medicine, National Institute of Homoeopathy, Block GE, Sector-III, Saltlake, Kolkata
⁵Central Council of Research in Homoeopathy, Kottaiyam
⁶Karunya University, Coimbatore, India
⁷Dr Abhin Chandra Homeopathic Medical College & Hospital, Bhubaneswar-751001, Odisha, India

^♦Corresponding author
Biswaranjan Paital, Laboratory of Redox Regulation, Department of Zoology, CBSH, Odisha University of Agriculture and Technology, Bhubaneswar, Odisha, India. Email: Biswaranjanpaital@gmail.com

ABSTRACT

Background: Obesity is one of the most common contributors to ill health, mortality and the reduced quality of life. Prevalence is increasing across the world especially in developed countries but now a days it is also increasingly noticed in developing countries including India due to change in life styles of the people. Garcinia cambogia (GC) is an herbal remedy, used for treatment of various health conditions including obesity. The aim of the study was to find out the effects of homeopathic formulation of G. cambogia in reducing the weight of obese patients and their lipid profile. Materials methods: A prospective, open randomized controlled trial was conducted. Thirty numbers of obese individuals having BMI ≥ 30 were divided into three comparable groups of 10 in each group receiving either GC3x (Decimal scale), GC 6c (Centesimal scale) or placebo in the form of 4 globule thrice a day for three months. The medicine and dilutions were prepared according to the homoeopathic principles. Their weight, total cholesterols, triglycerides, lowdensity lipoproteins, very low-density lipoproteins and high-density lipoproteins were measured, before and after treatment time point. Result: It was observed that GC 3x and GC 6c has significant reduction effects on weight (P <0.001) as well as in lipid profiles (P <0.001) in comparison to control group. G. cambogia prepared homeopathically in 3x and 6C potencies may be prescribed for significant reduction in weight and lipid profiles in obese patients. The initial diarrhea and constipation in certain study individuals required no medicinal intervention. Conclusion: Homoeopathic formulations from Garcinia cambogia especially at 6 c potency are highly beneficial for the management of body weight and lipid profile in obese subjects. Another randomized study with large sample size is suggested.

Keywords: Obesity, Garcinia cambogia, lipid profile, randomized controlled trial, homeopathic formulation

Medical Science, 2020, 24(103), 1000-1009

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