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Volume 24, Issue 103, May - June, 2020

Evaluation of treatment outcomes for Tuberculosis patients during 10 years

Masoud Amiri1, Mehdi Naderi Lordjani2♦, Hassan Askarpour3, Dariush Bastam4, Abuzar Shirazi5, Sajjad Rahimi Pardanjani6, Mohammad Moradi2, Seyedeh Reyhaneh Mansouri2

1Department of Statistics and Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2Department of Disease Management, Deputy of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
3Department of Disease Management, Deputy of Health, Yasuj University of Medical Sciences, Yasuj, Iran
4MSc of epidemiology, Yasuj University of Medical Sciences, Yasuj, Iran
5Department of Statistics and Epidemiology, Faculty of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
6Department of Statistics and Epidemiology, Faculty of Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

♦Corresponding author
Department of Disease Management, Deputy of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran; Email: lordejani@yahoo.com

ABSTRACT

Background and purpose: Tuberculosis is one of the most common infectious diseases in the world that can affect various organs including the lungs. Currently it is one of the major causes of death and disability, especially in developing countries. The aim of this study is to analyze the outcome of treatment for tuberculosis patients in Chaharmahal & Bakhtiari province during the years 2007- 2017. Materials and Methods: This is a descriptive-analytic study of historical cohort. Data on type of treatment, outcome of treatment, demographic and epidemiological characteristics were collected by referring to patients' health records through Health Department. Data were analyzed by SPSS v.20 using chi-square, Kruskal-Wallis and logistic regression tests at the 0.05 level. Results: The number of patients was 342 who were studied during 11 years from 2007-2017. 51.2% were female and 48.8% were male. The mean age of the patients was 49.79 ± 21.66 years. 1.2% of patients were infected with HIV. The outcome of treatment for a total of 342 patients with tuberculosis, 304 (88.9%) were successfully treated and eventually recovered. Of the 38 patients who had unsuccessful treatment, 22 died during the course of treatment and 16 patients had treatment failure and absenteeism. The highest treatment failure, absenteeism, and death were seen in the age group 65 and older. There was a significant relationship between age (p <0.0001), gender (p = 0.01), history of imprisonment (p <0.0001) and type of disease (p <0.0001) with treatment outcome. Conclusion: To achieve desirable outcome of treatment, comprehensive support, supply of drugs needed for TB control, need to improve DOTS strategy and planning for timely screening and identification of patients especially in high risk groups.

Keywords: Treatment Outcome, Tuberculosis, Epidemiology, Chaharmahal & Bakhtiari

Medical Science, 2020, 24(103), 1749-1756
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