Volume 24, Issue 102, March - April, 2020

The relationship between Dyspepsia and Non-Alcoholic Fatty Liver Disease: A case-control study

Rasoul Shafiezadeh¹, Seyed Saeid Esmaeili Saber^2♦, Seyed Moayed Alavian³, Mohammad Gholamiphesharaki⁴, Asie Poorasar⁵

¹MD, Department of Traditional Medicine, Faculty of Traditional Medicine, Shahed University of Medical Sciences, Teheran, Iran
²PhD, Department of Traditional Medicine, Faculty of Traditional Medicine, Shahed University of Medical Sciences, Teheran, Iran
³Professor of Gastroenterology and Hepatology, Baqiatallah Research Center for Gastroenterology and liver disease, Baqiatallah University of Medical Science, Tehran, Iran
⁴PhD, Assistant Professor of Biostatistics, Biostatistics Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Islamic Republic of Iran
⁵MD, Department of Traditional Medicine, Faculty of Traditional Medicine, Tehran University of Medical Sciences, Teheran, Iran

^♦Corresponding author
PhD, Department of Traditional Medicine, Faculty of Traditional Medicine, Shahed University of Medical Sciences, Teheran, Iran Email: seyedsaeidesmaeilisaber@gmail.com

ABSTRACT

Background and Objective: Non-alcoholic fatty liver is one of the most common non-infectious diseases in the liver, which is currently increasing prevalence in Iran and in the world. According to WHO recommendations for liver and related diseases, as well as identification of factors affecting non-alcoholic fatty liver, this study was conducted to investigate the association of Dyspepsia with non-alcoholic fatty liver. Material and Methods: This case-control study was conducted on patients referred to an ultrasound center in Isfahan, Iran during January to May 2018. In this study, ultrasound was used to diagnose non-alcoholic fatty liver and ROMEIII questionnaire for Dyspepsia diagnosis, and SPSS 21 software was used to analyze the data. Results: This study was performed on 190 subjects including 70 (37%) women and 120 (63%) men with an average age of 40 years with a standard deviation of 15 years. The results of this study showed that bloating (OR = 3.5, P-value = 0.001) and Dyspepsia (OR = 2.7, P-value = 0.002) is related to non-alcoholic fatty liver. Further analysis based on the decision tree showed that at the age of 29 years, having dyspepsia is a sign of a significant in the incidence of non-alcoholic fatty liver. This means that at the age of 29, Dyspepsia can be a sign of non-alcoholic fatty liver. Conclusion: Given that the results of this study showed that dyspepsia is very effective in predicting nonalcohol fatty liver, especially at the age of 29 years, it can be used as a quick, inexpensive and effective method for identifying or Suspecting non-alcoholic fatty liver and also treating it.

Keywords: Non-alcoholic fatty liver, Traditional Iranian Medicine, Dyspepsia

Medical Science, 2020, 24(102), 587-593

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