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Volume 21, Issue 88, November – December, 2017

About the Cover

Many preclinical trails on laboratory rats have well demonstrated the effects of unpredictable stressors that they produce behavioral and neurochemical alterations. Chronic stress produces the alteration in serotonergic transmission it has potential to increase the responsiveness to drug challenges and novel stressors to behavioral and neurochemical alteration. The present study was performed to determine the antidepressant potential of methylphenidate in animal model of chronic mild stress. The experimental case-control study was conducted in April 2015 at the Department of Biochemistry, University of Karachi and comprised male rats. Average weight rats were randomly divided into two equal groups, animal of stressed group were exposed to CMS. Animals of unstressed and stressed group were administrated with methylphenidate at dose 1.0 mg/kg/day for 14 days 1 hour before the animals exposed to CMS. Behavioral anxiolytic assessments were done by using light/dark transition and elevated plus maze apparatus models. CMS exposed animals showed behavioral deficits, which recovered by the repeated administration of methylphenidate treatment. Animals showed anxiogenic deficit on repeatedly exposure to stress as compared to unstressed animals which were attenuated by repeated administration of methylphenidate.

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PERSPECTIVE

Particulate matter air pollution and cardiovascular disease

Neil K. Agarwal, Prerna Sharma, Shashi K. Agarwal

Particulate matter air pollution, both indoor and outdoor, although traditionally causally associated with pulmonary disease, is now being increasingly implicated in cardiovascular disease and mortality.

Medical Science, 2017, 21(88), 270-279

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RESEARCH

Inhibition of unpredictable chronic mild stress induced anxiogenic condition by the repeated administration of methylphenidate in male rats

Muhammad Farhan, Safia Habib, Fatima Riaz, Sana Wali

Many preclinical trails on laboratory rats have well demonstrated the effects of unpredictable stressors that they produce behavioral and neurochemical alterations. Chronic stress produces the alteration in serotonergic transmission it has potential to increase the responsiveness to drug challenges and novel stressors to behavioral and neurochemical alteration.

Medical Science, 2017, 21(88), 280-286

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CASE STUDY

Broken synthetic tracheostomy tubes presenting as a foreign body in airways – Rare Case Series & Review of the literature

Sahoo Arpita Krishna, Ray Sundar Chinmaya, Priyadarshini Raisa

Tracheo-bronchial foreign body aspiration is a life threatening condition that can be seen in all age groups. Tracheostomy is a common lifesaving airway procedure. This procedure is although safe, early and late complications are known to occur.

Medical Science, 2017, 21(88), 287-293

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ANALYSIS

Dietary intake of female patients with renal failure in Al-Hassa Province, East of Kingdom of Saudi Arabia

Najat Ali Al-Abbad

The aim of this study was to assess the dietary intake of female patients with renal failure in Al-Hassa Province, east of Saudi Arabia, and to study the effect of some variables on dietary intake of the patients.

Medical Science, 2017, 21(88), 294-304

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RESEARCH

The return of the bilateral neck exploration for primary Hyperparathyroidism

Beatriz de Rienzo-Madero, Gabriel Kraus-Fischer, Carlos Toledo-Toral, Daniel Kajomovitz-Bialostosky, Manuel Muñoz-Juarez, Eduardo Moreno-Paquentin, Enrique Luque de Leon, David Caba, Fernando Cordera, Rodrigo Arrangoiz

We recommend the use of a radio guided bilateral neck exploration with the evaluation of the functionality of the four parathyroid glands to determine which should be excised for the management of primary hyperparathyroidism (PHPT).

Medical Science, 2017, 21(88), 305-316

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ANALYSIS

Phenotypic differentiation of class A and class B Carbapenemases in Enterobacteriaceae

Savitha Hiremath, Renushri BV, Nagaraj ER

Appropriate detection of Carbapenem Resistant Enterobacteriaceae (CRE) is vital for patient care in order to institute correct therapeutic options. Molecular techniques can easily differentiate classes but the need of the hour is a rapid practical phenotypic method which can differentiate KPCs and MBLs in Enterobacteriaceae.

Medical Science, 2017, 21(88), 317-321

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CASE REPORT

Monomorphic adenoma of base of tongue- a rare case report & review of literature

Sahoo Arpita Krishna, Ray Sundar Chinmaya, Dash Rajat, Sarangi Kaushik

Monomorphic adenoma is a rare benign salivary gland tumour of epithelial origin representing <2% of all tumours in general population and more than 80% of them arise in major salivary glands, mostly in the parotid gland and rarely in upper lip or buccal mucosa.

Medical Science, 2017, 21(88), 322-328

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ANALYSIS

Histological and electron microscopic examination of the effect of Dexketoprofen Trometamol on liver in rats

Arzu Esen Tekeli, Hatice Yağmurdur, Erçin Öngen, Ahmet Tekeli, Gülnur Take, Deniz Erdoğan, Beyazit Dikmen

The current study was performed for histological and electron microscopic examination of the effects of different doses of dexketoprofen trometamol on liver in rats.

Medical Science, 2017, 21(88), 329-335

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Does emotional intelligence affect peer support of nursing students?

Cinar-Pakyuz S, Dedeli-Caydam O, Sevgi-Dogan E, Deniz D

This study was conducted to assess the relationship between peer support and emotional intelligence as descriptive and correlation. Sample of the study consisted of 417 nursing students available and enrolled to Manisa Celal Bayar University Faculty of Health in academic year 2014-2015 and accepted to participate in the research.

Medical Science, 2017, 21(88), 336-347

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