Ag (I) complexes were prepared for a series of NHC substituents. Firstly, NHC precursors (1-9) were synthesized. In the second
step, Ag (I) -NHC complexes (10-15) were synthesized. Structure of silver (I) N-heterocyclic carbene complexes was analysed using
1H- and 13C-NMR spectroscopy. The activity of synthesized and characterized silver complexes on mycotoxin producing fungi and
biofilm-forming Gram negative or positive bacteria and Candida albicans was investigated. As a result, it was determined that the
most effective compound was 14, 15 and 13 respectively. Especially, compound 14 has been shown to have a high effect (12-
15mm/16-64µgmL-1) against Escherichia coli ATCC 35218, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 35032,
Listeria monocytogenes ATCC 19112, Candida albicans ATCC 10231, Aspergillus parasiticus NRLL 502. The results of antimicrobial
activity and microfungus micelle development were also found to be compatible
Keywords: Silver (I) N-Heterocyclic Carbene Complexes, Mycotoxin, Fungi, Biofilm, Microorganisms