Volume 14, Issue 34, July - December, 2020

Current developments of potentially significant Triazole derivatives

Mohammad Asif

Department of pharmacy, GRD (PG) IMT, Dehradun, India

ABSTRACT

Heterocyclic compounds analogues have attracted strong interest due to their useful pharmacological properties. Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. The small triazole nucleus is present in various compounds that possess various types of biological activities, such as, anti-microbial, antibacterial, antifungal, antiviral, anti-malarial, anti-tumor, anthelmintic, antileishmanial, anticonvulsant, antidepressant, antihypertensive, analgesic, anti-inflammatory and hypoglycemic properties. Scientists develop a lot of new compounds related to this moiety and screened them for their different pharmacological activities to get a molecule which have good pharmacological activity and lesser side effect. This reviews attempted the various developments in biological activities of triazole derivatives.

Keywords: Triazoles, heterocyclic, anti-microbial, anti-malarial, anticancer, biological activities.

Drug Discovery, 2020, 14(34), 197-211

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