Polypharmacy is common in the elderly. It continues to increase, despite its known association with increased morbidity and mortality. It
increases the risk of inappropriate use of medications, nonadherence, and adverse effects. Patients with polypharmacy also experience a
decline in the activities of daily living. It also raises health care costs. Elderly hypertensives are at particular risk for polypharmacy. This
stems from the need for multiple anti-hypertensive drugs for proper control of hypertension in this population, complicated by a host
of co-morbid conditions such as arthritis, heart disease, cancer, and diabetes mellitus – all requiring concomitant treatment. Health care
professionals should be congnizant of the risks of polypharmacy. Physicians need to monitor patient both prescription and nonprescription drug treatment periodically and educate both patients and their families on their proper usage.
Keywords: Polypharmacy, Adverse drug effects, Hypertension, Elderly