Volume 1, Issue 1, 2017

Adulterations of parenteral drugs: Desired health dealt hazard

Amnah Jahangir¹, Amna Shah¹, Atta Abbas^2,3♦

¹ Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan
² Department of Pharmacy, Clifton Hospital, Karachi, Pakistan
³ Department of Pharmacy, Health and Well Being, Faculty of Applied Sciences, University of Sunderland, England, United Kingdom

^♦Corresponding author
Atta Abbas, Advisory Board Member, Department of Pharmacy, Clifton Hospital, Karachi, Sindh, Pakistan, Tel: 0092-321-2643077; Email: bg33bd@student.sunderland.ac.uk

ABSTRACT

Parenteral preparations are those pharmaceutical preparations which are directly released in the blood stream without passing through hepatic metabolism. Any contamination in the preparation has the potential to risk a health hazard to the patient. Since these preparations are more prone to contamination they require critical approaches for maintenance of their integrity. Mal-dispensing practices and poor adherence to storage conditions would contaminate the drug. The drugs act 1976 defines an adulterated drug as one which is either contaminated or by any means injurious to health. Whereas, contaminated drug may lead to serious repercussions such as anaphylactic shock, sepsis, allergic reactions and at times, death. In order to avoid these adverse reactions, acquainted personnel coupled with good manufacturing and dispensing practices are essential which can ensure the integrity of drug from sterile area to the blood stream of the patient thereby avoiding any health promoting or desiring drug to hazard dealing one.

Keywords: Adulteration; Parenteral; Pakistan

International journal of adulteration, 2017; 1: e2ijad3002

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DOI: https://doi.org/10.54905/disssi.v1i1.e2ijad3002

Published: 27 October 2017