SLE (Systemic lupus erythematosus) is an autoimmune condition defined by autoantibody generation, immune complex accumulation, anda diverse set of clinical signs and symptoms. SLE is an immunological condition where the body's immune system mistakenly attacks the body's own tissues, causing widespread inflammation and tissue damage in the affected organs. According to an approx calculation, there are 161,000 people with proven SLE and 322,000 as or suspected SLE. Interfaces between genetics, as well as interactions between environmental and genetic factors, should be evaluated as significant risk stratification drivers. It can affect anyone at any age, although it is about 10 times more common in women than in males, with young women between the ages of 15 and 44 being the most affected. SLE has the potential to harm a patient's overall mental, physical, and social abilities. The constraints that patients with SLE face might have an influence on their quality of life. Exercise is difficult for individuals with SLE due to a variety of real and perceived limitations. We also present a case study of a 14-year-old female with SLE, in which we discovered that basic in-bed mobility exercises, breathing and positioning techniques, and cardiovascular (aerobic) training are beneficial to SLE patients. Physiotherapy was also essential in improving their quality of life and reducing secondary problems.
Keywords: Systemic lupus erythematosus (SLE), Pleural effusion, Manual
positioning, Physiotherapy, Case report