Volume 26, Issue 124, June 2022

Role of High Resolution Computed Tomography (HRCT) in predicting critical disease in corona virus disease

Avinash Dhok¹, Prashant Onkar², Dhananjay Patrikar², Aditya Rakhunde³, Pooja Ladke^3♦, Aisha Lakhani³

¹M.D. (Radiodiagnosis), Professor and Head of Department, Department of Radiodiagnosis and imaging, NKP Salve Institute of Medical Sciences and Research Centre, Digdoh hills, Nagpur 440019, Maharashtra, India
²M.D. (Radiodiagnosis), Associate Professor, Department of Radiodiagnosis and imaging, NKP Salve Institute of Medical Sciences and Research Centre, Digdoh hills, Nagpur 440019, Maharashtra, India
³MBBS, Junior Resident, Department of Radiodiagnosis and imaging, NKP Salve Institute of Medical Sciences and Research Centre, Digdoh hills, Nagpur 440019, Maharashtra, India

^♦Corresponding author
Department of Radiodiagnosis and imaging, NKP Salve Institute of Medical Sciences and Research Centre, Digdoh hills, Nagpur 440019, Maharashtra, India

ABSTRACT

Introduction: In the present study, we correlate the oxygen requirement of adult patients infected with COVID-19 virus with 25 CT severity score and estimate clinical outcome in the COVID-19 infected patients. Materials and methods: An observational case control study of 123 symptomatic COVID-19 positive patients presented to our hospital was collected for 3 months (August 2020 to Oct 2020). All patients underwent plain HRCT scan on TOSHIBA Activion 16 slice CT. The study was approved by Institutional Ethics Research review board and informed consents were obtained from all COVID-19 infected patients. Results: In our study, the Mean age of the patients ranged from 51-60 years (69.9% males, 30.1% females). CT severity score was correlated positively with the oxygen requirements as well as with other parameters i.e. age and sex. CT score of more than or equal to 18 was associated with an increased mortality risk and found to be predictive of death both in univariate (HR, 8.33; 95% CI, 3.19–21.73; p < 0.0001) and multivariate analysis (HR, 3.74; 95% CI, 1.10–12.77; p = 0.0348). Conclusion: The COVID-19 clinical severity is highly correlated with the 25-point CT severity score. Our findings imply that a chest CT grading system can help predict COVID-19 disease fate and has a strong relationship with oxygen demand and intubation.

Keywords: COVID-19, SARS-CoV-2, high-resolution computed tomography, CT severity score

Medical Science, 2022, 26, ms219e2082

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DOI: https://doi.org/10.54905/disssi/v26i124/ms219e2082

Published: 13 June 2022