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Volume 25, Issue 111, May 2021

About the Cover

Background: Cerebral chronic white matter (WM) microangiopathy is common with ageing and vasculopathy. It is known to be better detected on magnetic resonance imaging (MRI) compared to computed tomography (CT). Objective: To determine the detectability of WM microangiopathy on CT compared to MRI; utilizing a subjective visual approach. Material and Methods: A retrospective chart review was done in a private Jeddah’s hospital during 2020/2021. Four months of a local teleradiology practice archive was assessed for patients more than 40 years old who underwent both MRI and CT simultaneously. Those with known acute or other WM non-macroangiopathic findings were excluded. Detectability, size and location of supratentorial chronic WM changes were recorded for MRI and CT, considering MRI as the gold standard. Locations were categorized as periventricular, deep, juxtacortical and combination of all regions. Variable degrees of concordance between MRI and CT were assessed. Statistics were expressed in frequency distributions and mean +/-standard deviation. Comparison of categorical data by Fisher’s exact tests and between means by Mann Whitney U non-parametric test were performed (i.e., significant if P- values < 0.05). Results: A total of 35 cases were studied (62.9% males; mean age 40 ± 4.6 years).

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ANALYSIS

Validity of pleurodesis with bleomycin by pigtail versus chest tube in malignant pleural effusion

Ehab Sobhy, Saad Rabie Samra, Abdallah I Badr, Ahmed MA Bakry, Gaser Ali

Background: Pleural drainage is the preferred treatment for patients with symptomatic malignant pleural effusion. Insertion of a large bore chest tube for drainage prior to chemical pleurodesis is a standard treatment procedure.

Medical Science, 2021, 25(111), 1020-1027

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CASE REPORT

A complex case of prosthetic joint infection post total knee replacement: A case report

Riddhi Jain, Anushree Pawar, Pratik Phansopkar, Om C Wadhokar, Neha Chitale

One of the strongest and most complicated joints in the body is the knee. The knee connects the bone of the thigh (femur) to the shin bone (tibia). The other bones that form the knee joint are the smaller bone that runs alongside the tibia and the knee cap

Medical Science, 2021, 25(111), 1028-1032

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ANALYSIS

Echinacea purpurea root extract modulates diabetes-induced renal dysfunction in rats through hypoglycemic, antioxidants, and anti-inflammatory activities

Zuhair M Mohammedsaleh, Haya MA Aljadani

Introduction: Diabetes (DIAB)-related renal dysfunction is one of the most severe complications of the condition, which comes to an end with chronic renal failure

Medical Science, 2021,25(111), 1033-1043

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Detectability of cerebral chronic white matter microangiopathy on CT compared to MRI: A teleradiology study

Amr M Ajlan, Ayman A Eskander, Turki A Alhazmi, Nahla Khamis Ibrahim, Ahmed Abduljabbar, Mohammad Wazzan, Khalid Khashoggi, Rani Ahmad, Ayman Esmaeil Elkashty

Background: Cerebral chronic white matter (WM) microangiopathy is common with ageing and vasculopathy. It is known to be better detected on magnetic resonance imaging (MRI) compared to computed tomography (CT).

Medical Science, 2021, 25(111), 1044-1051

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Acceptance of mHealth technologies among Auxiliary Nurse Midwives in Andhra Pradesh, India: A mixed method study

Prakash Babu Kodali, Shankar Das

Introduction: Frontline health workers such as auxiliary nurse midwives (ANMs) play an important role in implementation of mHealth programmes

Medical Science, 2021, 25(111), 1052-1060

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"Medical Student Syndrome" in Vietnamese psychology students

Thuy-Trinh Ngo-Thi, Gia-Phuoc Tran-Thien, Nhu-Thuyen Dang-Thi, Vinh-Long Tran-Chi

Medical student syndrome is related to health anxiety and the amount of specialized knowledge of students. This study conducted to examine medical student syndrome on Vietnamese psychology students when they are studying courses related to clinical psychology and psychotherapy

Medical Science, 2021, 25(111), 1061-1070

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Neonatal sepsis in association with birth weight, gestational age, and mode of delivery in Saudi Arabia: A systematic review and meta-analysis

Nazim Faisal Hamid, Muawia Elsayed Elkhider Ebrahim, Naif Mutkhan Tohaimer Alsharari, Alaa Saud M Alyasi, Mostafa Moheb Mostafa Rizk

Introduction: Neonatal sepsis is a worldwide health problem. Additionally, neonatal sepsis causes a great burden of morbidity and mortality in developing countries. Methodology: A systematic search in PubMed, Web of Science, Science Direct, and EBSCO databases, was conducted.

Medical Science, 2021, 25(111), 1071-1079

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CASE REPORT

Management of deciduous molar with missing permanent successor – A case report

Niharika Gahlod, Arun Sajjanar, Milind Wasnik, Sneha Khekade, Nilesh Rojekar, Harshita Shukla

Deciduous teeth are present in the oral cavity for limited period of time, normally they exfoliate and the successor teeth attain their respective position in the oral cavity

Medical Science, 2021, 25(111), 1080-1083

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Plexiform neurofibroma: An Arduous entity

Ayushi Singh, Anil Agrawal, Sunita Vagha

Plexiform neurofibroma being the uncommon variant of neurofibroma generally involves head and neck region. It arises from the proliferation of all neural elements

Medical Science, 2021, 25(111), 1084-1087

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Angioinvasion of anterior cerebral artery by rhinocerebral mucormycosis leading to intraparenchymal hemorrhage: A rare case report

Sameera Dronamraju, Shubham Nimkar, Smita Damke, Sachin Agrawal, Sunil Kumar

Rhinocerebral mucormycosis leading to intraparenchymal bleed is a rare entity. The objective of this case report is to highlight this unusual incidence in a case of mucormycosis

Medical Science, 2021, 25(111), 1088-1091

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RESEARCH

Predicting early mortality in treatment of patients with acute infectious pancreatitis using two surgical strategies

Kryvoruchko IA, Sykal MO, Yevtushenko OV

Background: To determine the prediction of mortality and to develop a mathematical model of severe acute pancreatitis designed to predict early mortality in patients with secondary pancreatic infection

Medical Science, 2021, 25(111), 1092-1105

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ANALYSIS

Comparison of del Nido Cardioplegia and blood Cardioplegia in isolated CABG patients

Baburhan Ozbek, Mehmet Coskun Aykac

Introduction: Effective myocardial protection ensures safe operation during cardiac surgery. In this study, blood cardioplegia, which is the most preferred myocardial protection method in isolated coronary artery bypass grafting (CABG) operations, was compared with del Nido cardioplegia.

Medical Science, 2021, 25(111), 1106-1110

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Identification of novel leads against Cystalysin of Treponema denticola to combat Periodontitis: A computational approach

Mahvish Khan, Saif Khan, Khurshid Ahmad, Mohtashim Lohani, Shafiul Haque, Hazza A Alhobeira, Ammar A Siddiqui, Shadab Mirza, Arshad Hussain

Present study attempts to determine efficient biogenic leads against proteolytic enzyme Cystalysin of Treponema denticola, a red complex pathogen, responsible for periodontitis. Cystalysin is known to play central role in the occurrence and progression of chronic generalized periodontitis.

Medical Science, 2021, 25(111), 1111-1116

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CASE REPORT

Physical and psychological response to physical rehabilitation in Coronavirus Disease-19 patient: A case report

Ahmed Abdelmoniem Ibrahim, Hisham M Hussein, Hamad Ali Hakami, Saud M Alrawaili, Gopal Nambi, Walid Kamal Abdelbasset

Corona virus disease-19 (COVID-19) has affected people of various age groups with symptoms ranging from asymptomatic mild, moderate to severe symptoms

Medical Science, 2021, 25(111), 1117-1122

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ANALYSIS

Medical specialty students’ perceptions, experiences, and barriers regarding online learning: A cross-sectional study during the covid-19 pandemic

Shaimaa Abdalaleem Abdelgeleel, Dalia Negm Eldin, Mahmoud Abdel Hameed Shahin

Objective: To investigate medical specialty students’ perceptions, experiences, and barriers regarding online learning as a new direction for education after the novel coronavirus (COVID-19) pandemic in Egypt

Medical Science, 2021, 25(111), 1123-1132

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Willingness and preference for using telehealth services among patients with depression

Bayaneh Amini, Leila R Kalankesh, Reza Ferdousi, Mostafa Farahbakhsh, Farhad Fatehi

Background: Depression is a common mental disorder for which telehealth services can provide support. The willingness to use these solutions among patients is among factors related to the use of such solutions

Medical Science, 2021, 25(111), 1133-1139

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The effect of depression and life quality of geriatric diabetic patients on their glycemic control levels

Berna Nilgun Ozgursoy Uran, Funda Sofulu, Elif Unsal Avdal, Gulbin Konakci, Yasemin Tokem, Julide Gulizar Yildirim, Gizem Arslan

Objective: This study was aimed to determine the effect of quality of life and depression on the levels of glycemic control in geriatric diabetic patients.

Medical Science, 2021, 25(111), 1140-1149

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Effect of argan oil (Argania spinosa) on hypercholesterolemic male rats

Jamilah M Hashemi, Salma A Alahmari

Hypercholesterolemia is a metabolic condition that related to the occurrence of atherosclerosis and cardiovascular diseases. This research aimed to demonstrate the efficacy of argan oil in improving hypercholesterolemia in male rats

Medical Science, 2021, 25(111), 1150-1158

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Prevalence and predictors of anemia among type 2 diabetic patients, single center study in Al-Madinah region, Saudi Arabia

Bayan Alalawi, Samyah Bukari, Yousef Al-Alawi, Raneem Alraheili, Rami Alharbi, Alaa Alraheili, Smaher Alhejaili, Salma Alalawi, Amerah Alalawi

Background: Anemia is severe and common in diabetic patients compared to nondiabetic. Patients with type II Diabetes Mellitus (DM) are twice more likely to have anemia than nondiabetic patients and it is considered as a key prognostic factor

Medical Science, 2021, 25(111), 1159-1166

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Interproximal caries assessment decision making and treatment among dental students and practitioners in Saudi Arabia

Waseem W Radwan, Dalal R Al Assadi, Latifah M Al Masaud, Amjad A Selayem, Hadeel A Al Amrani, Arwa K Al Ohali

Aim: This study aims to assess the knowledge and perception of dental students and practitioners. Moreover, to assess their restorative threshold, restorative technique, and knowledge of the materials used to treat interproximal caries in Saudi Arabia

Medical Science, 2021, 25(111), 1167-1172

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Knowledge, attitude and practice of antibiotic use and misuse among adults attending Primary health care in Arar city, Saudi Arabia

Amer Mohammed Alanazi, Fayez Sulobi G Alenezi, Talal Duhaim M Alanazi, Tariq Majed A Alhumaid, Sabry Mohammed Hammad, Amal Elwan Mohammed

Background: Antimicrobials are the communal drugs used in the developing countries. The irrational use of antimicrobial drugs is a huge problem on national health system

Medical Science, 2021, 25(111), 1173-1182

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CASE REPORT

Intractable Singultus: Atypical presentation of COVID 19

Dhruv Talwar, Sunil Kumar, Sparsh Madaan, Shivam Khanna, Akhilesh Annadatha

Singultus are involuntary manoeuvre that involve the reflex arc of swallowing and can be further divided into acute singultus (<48 hours) or persistent singultus (>48hours).

Medical Science, 2021, 25(111), 1183-1187

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Case report of Inflammatory linear verrucous epidermal nevus (ILVEN): Sentence or surmountable difficulty?

Liliia Hulei

In this report, we describe a case of Inflammatory linear verrucous epidermal nevus (ILVEN) that clinically and histologically mimicked Blaschkoid (linear) lichen planus, linear psoriasis, and other linear dermatoses, for could be diagnosed by histopathologic findings.

Medical Science, 2021, 25(111), 1188-1194

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Chronic pancreatitis with sinistral portal hypertension: A rare case report

Param Shah, Sourya Acharya, Raju Shinde, Vijendra Kirnake, Sunil Kumar, Vijay ALS

Due to its rarity as an etiology of massive upper gastrointestinal bleeding, left sided portal hypertension also known as “Sinistral portal hypertension” is often missed or diagnosed late

Medical Science, 2021, 25(111), 1195-1198

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ANALYSIS

Adverse effects of methotrexate in gestational trophoblastic neoplasia treatment

Tuan Vo, Giang Nguyen, Tho Pham, Bao Vo

Objective: Identify the incidence and related factors of elevated transaminases in low-risk gestational trophoblastic disease patients treated with methotrexate

Medical Science, 2021, 25(111), 1199-1205

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Awareness of gastroesophageal reflux disease among health specialties students at Umm al-Qura University in Saudi Arabia

Khalid A Alhazmi, Abdulrahman F Kabli, Salah M Bakry, Suhayb M Bakry, Mohannad T Hemdi

Background: Gastroesophageal reflux disease (GERD) is a common chronic gastrointestinal disorder. It is defined as a condition in which reflux of gastric contents causing symptoms and complications

Medical Science, 2021, 25(111), 1206-1212

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Validity of pediatric appendicitis score in predicting disease severity in pediatric acute appendicitis

Nguyen Thanh Hiep, Nguyen Cong Minh

Objective: This study aims to evaluate the validity of Pediatric Appendicitis Score in predicting disease severity of acute pediatric appendicitis

Medical Science, 2021, 25(111), 1213-1217

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Study the therapeutic effect of capsule CTHepaB on nude mice carrying human hepatocellular carcinoma cells infected with hepatitis B virus

Tran Duc Huu, Tran Thai Ha, Dau Xuan Canh, Đoan Quang Huy, Le Thi Tuyet, Pham Quoc Binh, Tran Thi Minh Tam, Nguyen Thi Bach Tuyet, Nguyen Quoc Huy, Dinh Thi Hong Minh

Objective: To assess the effect the therapeutic effect of CTHepaB capsules on nude mice carrying human hepatocellular carcinoma cells (HCC) infected with hepatitis B virus (HBV).

Medical Science, 2021, 25(111), 1218-1224

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Effectiveness of auricular acupressure and breathing exercises for smoking cessation

Tran Thai Ha, Pham Ba Tuyen, Đoan Quang Huy, Pham Hong Ngoc, Dao Huu Minh, Pham Quoc Binh, Tran Thi Minh Tam, Nguyen Thi Bach Tuyet, Nguyen Quoc Huy, Dinh Thi Hong Minh

Objective: To determine the effectiveness of auricular acupressure and breathing exercises in smoking cessation treatment and monitor their adverse drug reaction (ADR).

Medical Science, 2021, 25(111), 1225-1232

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Awareness and practice regarding contact lens wearing and related complications among Jazan University students; Saudi Arabia

Osama B Albasheer, Amani Osman Abdelmola, Amaal Hanani, Afnan Zogbhy, Asma Mrair, Fatimah Badawi, Sameera Hakami, Ghaidaa Abuhekmah, Lama Ayoub, Alanoud Hakami

Purpose: The aim of the study was to determine the knowledge, attitude and practice regarding contact lens wearing and to sketch out the common related complications among Jazan University students

Medical Science, 2021, 25(111), 1233-1240

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Protective role of TD0014 against sodium valproate-induced reproductive toxicity in male wistar rats

Tran Thai Ha, Pham Thi Van Anh, Pham Ba Tuyen, Mai Phuong Thanh, Nguyen Thi Huong Lien, Pham Quoc Binh, Pham Thuy Phuong, ,Đoan Quang Huy, Tran Thi Minh Tam, Nguyen Thi Bach Tuyet, Nguyen Quoc Huy, Dinh Thi Hong Minh

Sodium valproate (VPA), a common treatment of epilepsy and other diseases, is known to have severe toxic effects on testis both in experimental animals and in humans.

Medical Science, 2021, 25(111), 1241-1247

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