Volume 24, Issue 106, November - December, 2020

Correlation between microstructural changes evident on optical coherence tomography and use of perfluorocarbon liquids for repair of primary rhegmatogenous retinal detachment

Mohamed Amr Azab¹, Mostafa Hamed Nabih², Ayman Mohamed Khattab², Islam Abdallah Mohalhal^1♦

¹Research Institute of Ophthalmology, Ministry of High Education, Giza, Egypt
²Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt

^♦Corresponding author
Research Institute of Ophthalmology, Ministry of High Education, Giza, Egypt; Email: dr.islamabdallah@hotmail.com

ABSTRACT

Purpose: To describe optical coherence tomography (OCT) features of the macula after pars plana vitrectomy for treatment of primary rhegmatogenous retinal detachment with and without using perfluorocarbon liquids (PFCLs). Patients and methods: This study is a prospective randomized study. Thirty eyes of 30 patients with repaired primary rhegmatogenous retinal detachment by pars plana vitrectomy and gas injection, 15 eyes without adjuvant use of perfluorocarbon liquids (PFCLs) and 15 eyes with use of PFCLs, were investigated with OCT imaging using Spectralis HRA+OCT (Heidelberg Engineering, Heidelberg, Germany) and Amsler grid within a few weeks after the operation after absorption of intraocular gas. Results: Microstructural changes detected on OCT imaging of the macula were diffuse retinal thickening (DRT), epiretinal membrane (ERM), cystoid macular oedema (CME), outer retinal corrugations (ORC), subretinal fluid (SRF) and macular hole (MH). These changes were observed in 16 of 30 eyes (53.3%), 10 eyes (66.7%) in the group (without PFCL), and 6 eyes (40.0%) in the group (with PFCL), (p value = 0.143). PFCL use has no statistical significance in the incidence of OCT changes. There was no statistically significant difference in the final mean best corrected visual acuity between the two groups. Metamorphopsia was detected in 12 of 16 (75%) of eyes showing OCT changes. Conclusion: OCT changes occur commonly after vitrectomy for repair of primary rhegmatogenous retinal detachment and the use of PFCLs does not seem to affect the incidence of these changes.

Keywords: Rhegmatogenous retinal detachment, Optical coherence tomography, Pars plana vitrectomy, Perfluorocarbon liquids, Macula

Medical Science, 2020, 24(106), 4286-4294

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