Volume 24, Issue 105, September - October, 2020

Investigating the appropriateness of antibiotic usage and misuse for uncomplicated urinary tract infections (UTIs) in the clinics at King Abdul-Aziz Hospital (KAH) in Makkah, Kingdom of Saudi Arabia

Shahad Al-Ahmadi¹, Yosra Al-Hindi^2♦

¹Pharm D candidate, Faculty of pharmacy, University of Umm Al-Qura, Makkah, KSA. Email: shahadalahnadi1417@gmail.com
²Assistant Professor in clinical pharmacy, Faculty of pharmacy, University of Umm Al-Qura, Makkah, KSA. Email: yzhindi@uqu.edu.sa

^♦Corresponding author
Dr. Yosra Alhindi Assistant professor in clinical pharmacy department, Umm Alqura University, Makkah, Saudi Arabia, Contact ph: 00966504530609

ABSTRACT

Inflammation or infection of the urinary tract is considered to be a critical and common condition that can affect vast numbers of patients yearly. Inappropriate antibiotic prescriptions lead to an increased risk to patients whom can face bacterial resistance. The main aim was to investigate the frequency of this infection and the antibiotic-treatment schemes and errors. A retrospective study was done in three months' time period during 2019 in the out-patient and in-patient clinics at King Abdulaziz Hospital in Makkah (KAH) in the Kingdom of Saudi Arabia. In general, (1,556) subjects have been diagnosed with this infection, consisted of children (13.7%), grown-ups (77.5%), and seniors (8.9%) subjects. 88.7% was the total frequency of these subjects attended clinics. Widespectrum of empirical antibiotics was endorsed for 80% of the subjects. The total wide-spread of antibiotic endorsement with at least one type of error was 45.2% (children 52%, grown-ups 45%, and seniors 46%). The most common mistakes were found in dose (38%), length of the treatment (9%), repetition (5%), and the choice of the antibiotic (3.5%). Mistakes in the dosage were significantly higher in children. However, misfolds in the treatment duration were greater in the seniors. Urine cultures of positive results were found in 31.50 % of patients, with Escherichia coli at high rates (77%). In conclusion the findings showed a large degree of misuse use of antibiotics in the care of UTIs at King Abdulaziz Hospital in Makkah, Saudi Arabia.

Keywords: Urinary tract infection, antibiotics, Errors

Medical Science, 2020, 24(105), 3485-3493

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