Amyloidosis may occur as a familial disorder with dominant inheritance or as non-familial variant. Non familial amyloidosis is further
divided into primary amyloidosis, which occurs in the absence of other disorders but usually associated with multiple myeloma; and
secondary amyloidosis in association with disorders such as chronic infections and rheumatologic diseases. Only primary and familial
amyloidosis is commonly associated with a polyneuropathy. We present a case of a fifty-one year old female who presented with
recurrent pre syncopal attacks and neuropathy, and later on diagnosed as primary systemic amyloidosis.
Keywords: amyloidosis, familial, rheumatologic, polyneuropathy, infections