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Volume 1-2, Issue 3-6, September - October 2013

About the Cover

A total of 349 suspected cases were included in the study with 50 controls. Off these, there are 76 females (21.77%) and 273 males (78.23%) of HIV suspected cases with different age groups(19-60) have been collected, processed with quality controls and incorporated in present study, during the years of 2010-2012 in hi-tech diagnostic center, Chennai, Tamil Nadu India. All patients have been screened for routine, HIVp24 antigen, CD4&CD8 counting and HIV RNA quantification. The FDA approved medical devices have been applied for above diagnostic tests likes Sysmex 2000i, Roche Cobas Integra 400plus, FACS caliber system and Abbott2000rt respectively. High risk age groups (25-40 years) have been observed in males and females suspected cases and it were higher in males (71.26%) when correlative with females infected cases (21.4%). The actual viral load quantification were obtained as results in different ranges like 14.30% target not detected(TND),7.7%(< 40 copies/ml),5.5% 3 log10,15.5% 4 log10, 25% 5 log10, 14.30% 6 log 10, and 4.6% 8 log 10 respectively. According to viral load, the depletion of CD4 was absolutely observed with percentages of CD4/CD8 and CD3. The conclusion of the study is that the 4th generation assay most accuracy than current 3rd generation assay in HIV acute stage screening and it should introduce in feature.


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MEDICINE OF THE MONTH

Long-term breastfeeding is related with Intelligence

Balasubramanian J

Breastfeeding is the feeding of an infant or young child with breast milk directly from female human breasts. Breastfeeding makes babies smarter. According to researchers, children who were breastfed longer had higher scores on intelligence or IQ tests.

Medical Science, 2013, 1(3), 47

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REVIEWS

Trans-Cranial Doppler (TCD) in clinical practice in medical sciences: a review article

Upadhyay PK, Tiwary G

Trans cranial Doppler is a portable, repeatable, bed side investigation tool of immense importance but it has not been utilized to its full potentials in Medical Sciences even where it is available. A brief indications and role of TCD in different disorders are discussed.

Medical Science, 2013, 1(3), 48-52

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CASE REPORTS

Aggressive digital papillary adenocarcinoma: a case report

Bharath C

Aggressive digital papillary adenocarcinoma is a rare malignancy of eccrine sweat gland origin with propensity for metastasis and recurrence, occurring in men. The recognition of this tumor as a distinct clinicopathologicaleccrine sweat gland neoplasm is important because of the potential for aggressive local growth and distant metastasis.

Medical Science, 2013, 1(3), 53-54

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Fourteen wormian bones in an adult Indian skull – A rare case report

Sreekanth Tallapaneni, Chigurupati Namrata, Swathi Veliginti, Abishek Mogili, Shahzeb Zaman, Faraz Adil Hashmi

Multiple wormian bones are the prominent features of various cranial dystosis. The wormian bones are formations associated with insufficient rate of suture closure and regarded as epigenetic and hypostotic traits. It was reported that there exists racial variability among the incidence of these bones.

Medical Science, 2013, 1(3), 55-59

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Prolapse of ventricular shunt tube from rectum in a child with congenital hydrocephalus

Upadhyay PK, Tiwary Geeta

Shunt prolapse through anusis a rare complication of Shunting. It is fraught with further serious complications. Proper management with shunt tube exteriorization and followed by removal and reinsertion. Per anal prolapse and its treatment is described.

Medical Science, 2013, 1(3), 60-62

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RESEARCH

Antimicrobial effects of the chloroform and ethanolic leaf extracts of Dacryodes Edulis (G. Don) H.J. Lam, Garcinia Kola Heckel and Chrysophyllum Albidum G. Don on some test isolates

Idu M, Erhabor JO, Towuru GE

Dacryodes edulis, Garcinia kola, and Chrysophyllum albidum are well known plants used for traditional medicine in the treatment of various ailments and diseases. The crude extracts of these three plants were screened for their antimicrobial effects against some selected microorganisms; bacteria and fungi using an agar-diffusion method.

Medical Science, 2013, 1(3), 63-66

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MEDICINE OF THE MONTH

Harvard School of Public Health reveals 40% of Colorectal Cancers prevent by Colonoscopy Screening in Every Decade

Balasubramanian J

Colorectal cancer, commonly known as colon cancer or bowel cancer is a uncontrolled cell growth in the colon or rectum or in the appendix. Most colon cancers are adenocarcinomas (cancers that begin in cells that make and release mucus and other fluids).

Medical Science, 2013, 2(4), 7

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PERSPECTIVE

Testosterone replacement therapy for the males affected with XXY syndrome

Thiviyaaluxmi K, Elakkiya NR, Shivarangan S

XXY syndrome in males has been found in our society in the ratio of 1:500. It is a common condition, but often under diagnosed and undertreated. The indication of testosterone-replacement therapy (TRT) treatment requires the presence of low testosterone level.

Medical Science, 2013, 2(4), 8-9

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CASE STUDY

Hyper-reactive malarial splenomegaly: about a case

Redouane Roukhsi, Abdelilah Mouhcine, El Mehdi Atmane, Monsef Elabdi, Tahir Nebhani, Abdelghani El Fikri, M’Barek Mahfoudi

Malaria is one of the most severe public health problems worldwide. Hyper-reactive malarial splenomegaly ( HMS) is a form of severe malaria. The diagnosis was based on the exclusion of other causes of splenomegaly, immunity to malaria, splenomegaly of at least 10 cm, a high serum concentration of Ig M.

Medical Science, 2013, 2(4), 10-12

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RESEARCH

Role of intra operative ultrasonography for real time localization in operative procedures for surgery, brain surgery and spinal surgery

Upadhyay PK, Tiwary G

Intra operative ultrasonography guides the surgeon about exact intra operative position instantly and also defines the boundaries of mass lesion for excision during operation and also visualizes movement of lesion during surgery.

Medical Science, 2013, 2(5), 17-19

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Superior thyroid artery arising from the common carotid artery

Sreekanth Tallapaneni, Mahabhashyam Vijaya Kumar, Waqia Sultana, Shaik Karimuddin Abdullah, Mohammed Salman Ali

The neck dissection of a male cadaver revealed a thyroid gland having its left lobe supplied by a left superior thyroid artery arising from the left common carotid artery. There was a supra isthmic arterial arcade formed between the anterior branches of both the right and left superior thyroid arteries.

Medical Science, 2013, 2(5), 20-23

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Complications faced by Neurosurgeons in closure of abdomen for trans- abdominal neurosurgery done for Neurosurgical disorders

Upadhyay PK, Tiwary G

Single layered closure were done in 300 cases including 2000 cases of polypropylene closure in 100 infected cases and 100 uninfected cases .Out of 100 cases of vicryl mass closure faired badly as regards to post operative infection and sinus formation in infected cases.

Medical Science, 2013, 2(5), 24-25

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ANALYSIS

Risk factors for HIV seropositivity among first time blood donors in relatives for neurosurgical patients in north India

Tiwary G, Upadhyay PK

Exclusion of donors who are likely to be infected with HIV is a sound policy for improving blood safety and reducing operative cost. Factors associated with increased likely hood of HIV infection among newly recruited blood donors are identified and their feasibility as criteria for exclusion from donation is assessed

Medical Science, 2013, 2(6), 29-31

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RESEARCH

Detection of HIV p24 antigens, CD4/CD8 counts and HIV RNA quantification among HIV patients, at hi-tech center, in cosmopolitan city of Chennai, Tamil Nadu, India

Amirthalingam R, Pavalakodi VN

A total of 349 suspected cases were included in the study with 50 controls. Off these, there are 76 females (21.77%) and 273 males (78.23%) of HIV suspected cases with different age groups(19-60) have been collected, processed with quality controls and incorporated in present study, during the years of 2010-2012 in hi-tech diagnostic center, Chennai, Tamil Nadu India.

Medical Science, 2013, 2(6), 32-38

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