Volume 20, Issue 45, January - June, 2026

Synthesis and characterization of silver nanoparticles from Chryzopogon zizanioides root for its anti-microbial, anti-inflammatory, and anti-cancer activities

Pushparani DS^1♦, Keerthana M²

¹Department of Biochemistry, Asan Memorial Dental College & Hospital, Asan Nagar, Keerapakkam, Chengalpattu, 603105, Tamil Nadu, India.
²Department of Biochemistry, Dwaraka Doss Goverdhan Doss Vaishnav College, Arumbakkam, Chennai-600106, Tamil Nadu, India.

^♦Corresponding Author
Pushparani DS, Department of Biochemistry, Asan Memorial Dental College & Hospital, Asan Nagar, Keerapakkam, Chengalpattu, 603105, Tamil Nadu, India

ABSTRACT

The study aims to synthesize silver nanoparticles from aqueous extract of Chryzopogon zizanioides plant using Soxhlet Extraction method, and to evaluate its anti-microbial, anti-inflammatory, and anti-cancer activity potential. Chryzopogon zizanioides mediated silver nanoparticles exhibited strong anti-cancer, antiinflammatory, and anti-microbial activity. The percentage of inhibition of silver nanoparticles synthesised from Vetiveria zizanioides was found to be more effective at high concentration (67.85% for 80μL, and 72.85% for 100μL). The findings indicate that Chryzopogon zizanioides demonstrates encouraging pharmacological properties, and the synthesized silver nanoparticles was proven to have a strong antioxidant, anti-inflammatory, anti-bacterial, and anti-cancer properties. It would be useful in promoting research aiming at the development of new effective anti-cancer activity against breast cancer. Hence, the utilization of natural harmless materials like root extracts for nanoparticles synthesis offers various potential therapeutic uses in clinical settings for drug, and biomedical applications.

Keywords: Anti-cancer activity, Chryzopogon zizanioides, Nanotechnology, Silver nanoparticles.

Drug Discovery, 2026, 20(45), e11dd3069

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Published: 25 April 2026