Volume 1, 2012

About the Cover

Plants contain chemical compounds that may be in one way or another responsible for healing properties and other functions. Phytochemistry deals with the analysis of plant chemicals called natural products, and with changes occurring in such chemicals due to alterations in environmental conditions. Many plants have been used because of their antimicrobial traits, which are chiefly due to the synthesis of secondary metabolites. The present study is aimed to investigate the phytochemical and antibacterial activity of the medicinal plant Indigofera aspalathoides against Escherichia coli, salmonella typhi, shigella, and staphylococcus aureus. The initial screening of antibacterial activity for the plant extracts was studied using the ethanolic, hexane and diethyl ether extracts. The ethanolic extracts of Indigofera aspalathoides leaves showed prominent antibacterial activity against E.coli and salmonella typhi. The total soluble proteins analysed in control and extract treated E.coli exhibited protein synthetic machinery. The ethanolic, hexane and diethyl ether extracts produce very little changes in inhibiting shigella and not that much in staphylococcus aureus cultures. Our results indicate that the ethanolic extract of Indigofera aspalathoides leaves have potent antibacterial components against E. coli and salmonella typhi

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SPECIES OF THE MONTH

Species – the basic element of biology

Reshma M

Plants and animals compete and cooperate in their environment resulting in what is often described as a "Balance of Nature" within an ecosystem. Organisms thrive or perish within biomes depending on their ability to adapt. In 1850, Charles Darwin published The Origin of the Species in which he postulated that all plants and animals originated with a single cell and over time has evolved into the complex number of species that we know today.

Species, 2012, 1(1), 3-4

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RESEARCH

In silico Comparative Genomics of Treponema

Anjaneyulu k, Ashok .P. Patil, Desai PV

T. pallidum is one of the few human bacterial pathogens that have not been cultivated in vitro. This pathogens still remains the enigmatic pathogen, since few of its virulence factors have been identified and the pathogenesis of the disease is poorly understood.

Species, 2012, 1(1), 5-14

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Preparation and charecterization of PEG nanoparticle loaded with irinotican hydrochloride

Pragadeesh K, Balasubramanian J, Narayanan D, Shahul Hameed Maraicar K

Irinotecan Hydrochloride is an anticancer drug, a potent inhibitor of enzyme topoisomerase-1 activity. Its absorption is quite rapid in GIT, having a biological half life of about 6 – 12 hrs

Species, 2012, 1(1), 15-19

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Evaluate the Efficacy of Indigofera aspalathoides against Bacteria

Reshma M

Plants contain chemical compounds that may be in one way or another responsible for healing properties and other functions. Phytochemistry deals with the analysis of plant chemicals called natural products, and with changes occurring in such chemicals due to alterations in environmental conditions.

Species, 2012, 1(1), 20-22

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SPECIES OF THE MONTH

Diversity of species: a perspective

Reshma M

The diversity of species on Earth is incredible. There are more than 1.7 million species that have been discovered. Many species of plants and animals have evolved to depend on one another. For example, some plants can only be pollinated by a certain kind of bird or insect.

Species, 2012, 1(2), 25

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A review on medicinal value of Xi – Shu tree

Balasubramanian J, Narayanan N

Xi shu (Camptotheca acuminata) belongs to the Nyssaceae family and is a huge tree growing up to a height of 25 meters having thin reddish-brown bark and a small number of branches close to its apex. In China people have named this tree as the happy tree owing to its effectiveness in treating a number of ailments and colds.

Species, 2012, 1(3), 28-29

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